哮喘合并肺隐球菌病继发嗜酸细胞增多一例报告  

A case report of secondary eosinophilia in asthma complicated with pulmonary cryptococcosis

作　　者：范广婧 黄宏[1] 邹小英[1] 曾晶晶[2] 刘唐娟[1] 罗劲[1] Fan Guangjing;Huang Hong;Zou Xiaoying;Zeng Jingjing;Liu Tangjuan;Luo Jin(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Guangjci Medical University,Nanning 530021,China;Department of Pathology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院呼吸与危重症医学科,南宁530021 [2]广西医科大学第一附属医院病理科,南宁530021

出　　处：《国际呼吸杂志》2020年第11期843-846,共4页International Journal of Respiration

摘　　要：肺隐球菌病常发生于免疫缺陷患者,但近年来,肺隐球菌病在无免疫功能缺陷或基础疾病的人群中发病率逐年增加,糖皮质激素治疗为主要危险因素;哮喘患者长期激素治疗易继发真菌感染,多为曲霉菌感染,合并隐球菌罕见;哮喘常伴随嗜酸细胞升高,各种病因继发嗜酸细胞增多可致哮喘样发作症状,真菌感染继发嗜酸细胞增多,常见于曲霉菌感染(如变应性支气管肺曲菌病),隐球菌感染继发嗜酸细胞增多较为少见。本文就1例哮喘合并肺隐球菌病继发嗜酸细胞增多病例给予报道,以提高临床医师对该类疾病的认识。Pulmonary cryptococcosis often occurs in immunodeficiency patients,but in recent years,the incidence of pulmonary cryptococcosis has increased year by year in the population without immunodeficiency or basic disease,the main risk factor is glucocorticoid treatment.Asthma patients with long-term hormone treatment is prone to secondary fungal infection,mostly aspergillus infection,associate with cryptococcus rare.Asthma often accompanies by elevated eosinophils,various causes of secondary eosinophilia can cause symptom of asthma attacks.Fungal infection secondary eosinophilia,common in aspergillus infections(such as allergic bronchopulmonary aspergillosis),cryptococcus infection is rare.In here,we will report a case of secondary eosinophilia in asthma complicated with pulmonary cryptococcosis to improve the clinician′s understanding of this disease.

关 键 词：哮喘 嗜酸粒细胞增多 肺隐球菌病 乳胶凝集试验 

分 类 号：R519[医药卫生—内科学] R562.25[医药卫生—临床医学]