2009-2018年南宁市手足口病流行病学特征分析  

Epidemiological analysis of Hand-Foot-Mouth disease in Nanning City from 2009 to 2018

作　　者：周春丽[1] 黄婷[1] 梁家芝[1] ZHOU Chun-li;HUANG Ting;LIANG Jia-zhi(Record Room of Medical Department,Nanning Second People's Hospital,Nanning Guangxi,530031,China)

机构地区：[1]南宁市第二人民医院医务部病案室,广西南宁530031

出　　处：《职业与健康》2020年第8期1079-1081,1086,共4页Occupation and Health

基　　金：广西壮族自治区卫生健康委自筹经费科研项目(Z20170118)。

摘　　要：目的分析2009-2018年南宁市手足口病疫情流行病学及病原学特征,查找流行原因,为南宁市手足口病疫情防控工作提供参考依据。方法通过国家疾病预防控制信息系统及南宁市各医院卫生机构的传染病报告信息,获得2009-2018年南宁市手足口病疫情数据及病原学检测资料,采用描述流行病学方法对数据进行统计分析。结果2009-2018年南宁市累计报告手足口病病例469420例,其中重症病例4601例,病死数93例,年均发病率为719.20/10万。每年发病分布呈现高低2个高峰,主高峰在4-7月,次高峰在9-10月;性别分布中男女性别比为1.59∶1,男性发病高于女性;职业分布以0~4岁散居和托幼儿童为主,占发病总数的96.22%。地区发病率前3位分别为兴宁区(1194.77/10万)、西乡塘区(1196.85/10万)和良庆区(1052.42/10万),最低为横县(224.68/10万)。病原学检测结果分别为:肠道病毒71型(EV71)占总阳性数35.15%;柯萨奇A组16型(CoxA16)占21.75%;其他肠道病毒占43.10%;2010、2012、2014和2016年等偶数年份EV71检出率均较其他肠道病毒高。结论2009-2018年南宁市手足口病发病率逐年增高,以0~4岁散居儿童发病为主,偶数年份EV71病毒为优势病毒株,2016年开展EV71疫苗接诊后重症及死亡明显减少,应加强以EV71疫苗接种为重点的综合防控措施。Objective To analyze the epidemiological and etiological characteristics of Hand-Foot-Mouth disease(HFMD)epidemic situation in Nanning from 2009 to 2018,finding the epidemic causes,to provide scientific basis for the prevention and control of HFMD.Methods According to the National Information System for Disease Prevention and Control and the report information of infectious diseases from hospitals and health institutions in nanning,the epidemic situation and pathogen monitoring data of HFMD in Nanning from January 2009 to December 2018 were obtained,and the monitoring data were statistically analyzed by descriptive epidemiological method.Results From 2009 to 2018,469420 cases of HFMD were reported in Nanning,including 4601 severe cases and 93 died cases,with an average annual incidence rate of 719.20/lakh.There were two peaks in the annual distribution of the disease,the main peak was from April to July,and the secondary peak was from September to October.The ratio of male to female was 1.59:1,and the incidence of male was higher than that of female.The occupational distribution was mainly scattered children and kindergartens aged 0-4,accounting for 96.22%of the total incidence.The incidence rate of the top 3 regions were Xingning District(1194.77/lakh),Xixiangtang District(1196.85/lakh)and Liangqing District(1052.42/lakh),the lowest being Hengxian(224.68/lakh).The results of etiology test were as follows:Enterovirus 71(EV71)accounted for 35.15%of the total positive number;Coxsackie a group 16(CoxA16)accounted for 21.75%;other enteroviruses accounted for 43.10%.The detection rate of EV71 in even years such as 2010,2012,2014 and 2016 was higher than that of other enteroviruses.Conclusion From 2009 to 2018,the incidence of HFMD increased year by year in Nanning.The majority of the cases were scattered children aged 0-4 years old.EV71 virus in even-numbered years was the dominant virus strain.Severe disease and death were significantly reduced after EV71 vaccine treatment in 2016,and comprehensive prevention and con

关 键 词：手足口病 流行病学特征 重症手足口病 肠道病毒71型 

分 类 号：R181.81[医药卫生—流行病学]