益气滋阴消瘀方联合西药治疗进展性脑梗死合并2型糖尿病60例  

Sixty Cases of Progressive Cerebral Infarction Combined with Type 2 Diabetes Treated with Qi-Boosting and Yin-Nourishing and Stasis-Removing Decoction Combined with Western Medicine

作　　者：赵海云[1] 陈贞 陈桂香[1] 杨悦靖 康伟娟 贾婕 刘鑫 ZHAO Hai-yun;CHEN Zhen;CHEN Gui-xiang;YANG Yue-jing;KANG Wei-juan;JIA Jie;LIU Xin(Huanghua People's Hospital,Huanghua,Hebei,China,061100)

机构地区：[1]黄骅市人民医院,河北黄骅061100

出　　处：《河南中医》2020年第7期1062-1065,共4页Henan Traditional Chinese Medicine

基　　金：河北省沧州市2017年度重点研发计划指导项目(172302205)。

摘　　要：目的:观察益气滋阴消瘀方联合西药治疗进展性脑梗死合并2型糖尿病的临床疗效及其对患者神经功能和认知功能的影响。方法:将120例进展性脑梗死合并2型糖尿病患者按照随机数字表法分为对照组和观察组,每组各60例。对照组者给予常规西药及羟乙基淀粉注射液,观察组在对照组的基础上加服自拟益气滋阴消瘀方治疗。比较两组患者的临床疗效,观察两组患者治疗前后血糖水平、神经功能[美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)、改良爱丁堡-斯堪的纳维亚卒中量表(modified edinburgh-scandinavian stroke scale,MESSS)]及认知功能[简易智力状态检查量表(mini-mental state examination,MMSE)、Barthel指数]评分变化情况。结果:对照组有效率为78.33%,观察组有效率为88.33%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后空腹血糖、餐后2 h血糖低于本组治疗前,且观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后NIHSS、MRS评分低于本组治疗前,且观察组低于对照组;两组患者治疗后MMSE、Barthel指数评分高于本组治疗前,且观察组高于对照组,差异均有统计学意义(P<0.05)。结论:益气滋阴消瘀方联合西药可有效改善进展性脑梗死合并2型糖尿病患者的血糖水平、神经功能和认知功能。Objective:To observe the clinical efficacy of Qi-Boosting and Yin-Nourishing and Stasis-Removing Decoction combined with Western medicine on progressive cerebral infarction combined with type 2 diabetes and its influence on neurological function and cognitive dysfunction of patients.Methods:A total of 120 patients with progressive cerebral infarction combined with type 2 diabetes were randomly divided into the control group and the observation group according to the random number table method,with 60 cases in each group.The control group was given conventional Western medicine and hydroxyethyl starch injection,while the observation group was additionally given Qi-Boosting and Yin-Nourishing and Stasis-Removing Decoction on the basis of the control group.The clinical efficacies of the two groups were compared.The score changes of the blood glucose level,neurological functions,including national institute of health stroke scale and modified Edinburgh Scandinavian Stroke Scale(MESSS),cognitive impairment,including mini mental State Examination(MMSE)and Barthel index,were measured.Results:The effective rate of the control group was 78.33%,and that of the observation group was 88.33%.The difference between the two groups was statistically significant(P<0.05).The fasting blood glucose and postprandial 2 h blood glucose of the two groups after the treatment were lower than those of the same group before treatment,and the above indexes of the observation group were lower than those of the control group,and all the differences were statistically significant(P<0.05).The NIHSS,MRS scores of the two groups were lower than those of the same group before treatment,and the above indexes of the observation group were lower than those of the control group,and all the differences were statistically significant(P<0.05).The MMSE and Barthel index scores of each of the two groups was higher than that of the same group before the treatment,and the Barthel index score of the observation group was higher than that of the control group,a

关 键 词：进展性脑梗死 2型糖尿病 益气滋阴消瘀方 羟乙基淀粉注射液 

分 类 号：R259.871[医药卫生—中西医结合]