妊娠合并新型冠状病毒肺炎临床特征分析  

Analysis of clinical characteristics of pregnancy women with COVID-19

作　　者：余楠 李伟[1] 方紫璇 林星光[1] 王少帅[1] 刘燕燕[1] 刘海意[1] 邓东锐[1] 陈素华[1] 曾万江[1] 冯玲[1] 乌剑利[1] YU Nan;LI Wei;FANG Zi-xuan;LIN Xing-guang;WANG Shao-shuai;LIU Yan-yan;LIU Hai-yi;DENG Dong-rui;CHEN Su-hua;ZENG Wan-jiang;FENG Ling;WU Jian-li(Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China)

机构地区：[1]华中科技大学同济医学院附属同济医院妇产科,武汉430000

出　　处：《中国临床医学》2020年第3期361-365,共5页Chinese Journal of Clinical Medicine

基　　金：国家自然科学基金(81701530,81701476);湖北省自然科学基金(2017CFB626).

摘　　要：目的:探讨妊娠合并新型冠状病毒肺炎(COVID-19)患者的流行病学特点、临床特征及诊断。方法:回顾性分析2020年1月15日至2020年2月15日在华中科技大学同济医学院附属同济医院收治的22例妊娠合并COVID-19患者的临床资料,分析其流行病学特点、临床及放射学特征和实验室数据。结果:22例患者临床表现中有发热10例(45.45%)、咳嗽5例(22.73%)、呼吸急促1例(4.55%)和腹泻1例(4.55%)。21例(95.45%)为普通型,1例(4.55%)为重型。实验室检查中,淋巴细胞降低14例(63.64%),D-二聚体增高22例(100%)。胸部CT检查均示典型的COVID-19表现,病原学核酸检测阳性率40.91%(9/22)。结论:孕妇患COVID-19的临床特征和实验室检查与非妊娠成人患者相似,相对于病原学检查,胸部CT检查快速安全且敏感性高,更适合COVID-19流行地区产科急诊住院患者的初筛,同时能监测病情进展,有助于COVID-19孕妇的筛查、诊断及监测。Objective:To explore the clinical feature,diagnosis,treatment,and pregnancy outcome of pregnant women with novel coronavirus pneumonia(COVID-19).Methods:Epidemiological,radiological features,laboratory data,treatment and maternal and fetal outcomes of 22 pregnant women with COVID-19 who had been admitted to Tongji Hospital of Huazhong University of Science and Technology during January 15 to February 15,2020 were retrospectively analyzed.Results:In clinical manifestations of pneumonia,10 had fever(45.45%),5(22.73%)coughing,1(4.55%)shortness of breath and 1(4.55%)diarrhea.In laboratory examination,lymphocyte decreased in 14 cases(63.64%),and D-dimer increased in 22 cases(100%).CT showed pulmonary infection and the positive rate of nucleic acid test results was 40.91%.Conclusions:The clinical characteristics of these patients with COVID-19 during pregnancy were similar to those of reported non-pregnant adults with COVID-19.Compared to the etiology test,chest CT is faster in detection and safer for pregnancy and more suitable for the screening of emergency obstetric inpatients in epidemic areas.It can also monitor the progress of the disease,which is helpful for screening,diagnosis and monitoring of pregnant women with COVID-19.

关 键 词：妊娠 新型冠状病毒肺炎 影像学诊断 临床特征 

分 类 号：R563.1[医药卫生—呼吸系统]