血余炭药理作用及作用机制的研究进展  

Research Progress on Pharmacological Action and Mechanism of Charred Human Hair

作　　者：刘帅 李沙沙 张登禄 Liu Shuai;Li Shasha;Zhang Denglu(Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250021,China;Shandong Provincial Hospital Affiliated to Shandong Frist Medical University,Jinan 250021,China)

机构地区：[1]山东中医药大学附属医院,济南250021 [2]山东第一医科大学附属省立医院,济南250021

出　　处：《中国药事》2020年第5期585-588,共4页Chinese Pharmaceutical Affairs

基　　金：青年科学基金项目(编号81700592)。

摘　　要：目的:为血余炭的深入研究提供参考。方法:以"血余炭""药理作用""作用机制"为关键词,检索1982年4月-2018年9月在中国知网、万方、维普等数据库中的相关文献,归纳总结后进行综述。结果:检索到相关文献102篇,其中有效文献24篇。血余炭的药理作用包括凝血止血、抗菌抗炎、促进疮面愈合、血管栓塞及促进毛发生长作用,这些作用可能是血余炭通过自身理化性质、降低环磷酸腺苷含量、抑制细菌生长、降低白细胞介素-6水平、促进疮面表皮细胞及胶原修复、诱发血栓形成、调节毛囊生长周期等一系列机制而实现。结论:血余炭的药理作用广泛,但其作用机制并未详细阐明,还亟需进一步深入研究。Objective: To provide reference for further research and development of charred human hair. Methods: The keywords of "Charred Human Hair", "pharmacological action" and "mechanism of action" were used to search and summarize relevant literature in databases such as CNKI, Wanfang and VIP from April, 1982 to September, 2018. Results: 102 references were found, and 24 of which were valid. Charred human hair’s pharmacological effects include: blood coagulation hemostasis effects, antibacterial and anti-inflammatory effects, promoting wound healing, vascular embolization and promoting hair growth. Because of its physical properties, these effects may lower ring adenosine phosphate content, inhibit bacterial growth, lower levels of interleukin-6, promote restoration of the wound epidermis cells and collagen, induce thrombosis, and adjust the hair follicle growth cycle or other mechanism. Conclusion: The pharmacological action of Charred Human Hair is extensive, but the mechanism of action has not been elucidated in detail. Further research is urgently needed.

关 键 词：血余炭 药理作用 作用机制 

分 类 号：R96[医药卫生—药理学]