Step-growth polymerization of traptavidin-DNA conjugates for plasmonic nanostructures  

作　　者：Young-Youb Kim Yongbin Bang Dayoung Lee Mingyu Kang Yoon-Kyu Song 

机构地区：[1]Graduate School of Convergence Science and Technology,Seoul National University,Seoul 08826,Republic of Korea [2]Advanced Institutes of Convergence Technology.Gyeonggi-do 16229,Republic of Korea

出　　处：《Chinese Chemical Letters》2020年第5期1137-1140,共4页中国化学快报（英文版）

基　　金：supported by the Brain Research Program(No.2016M3C7A1904987)through the National Research Foundation of Korea(NRF)。

摘　　要：Here,we use two important biomaterials,protein and DNA,to construct self-assembled linear nanostructures through Watson-Crick base-paring of DNAs.We apply a simple magnetic separation method to purify traptavidin-DNA co njugates,and demonstrate synthesis of linear arrays of traptavidinDNA conjugates via the step-growth polymerization approach with pre-determined DNA sequences.Using the traptavidin-DNA array as a template,we assemble gold nanoparticles to form linear plasmonic nanostructures in a programmable manner.The traptavidin-DNA conjugates thus provide a convenient platform for one-dimensional assembly of biotinylated nanomaterials for many biomedical applications from drug delivery to bio-sensing.

关 键 词：Protein-DNA conjugate DNA nanostructure Supramolecular assembly Traptavidin Plasmonic nanostructure 

分 类 号：TB383.1[一般工业技术—材料科学与工程]