牦牛生长激素受体基因exon 5序列SNP多态性分析  

SNP Polymorphism Analysis on Exon 5 of Growth Hormone Receptor Gene of Yak

作　　者：金鑫燕 JIN Xin-yan(State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Key Laboratory of Plateau Grazing Animal Nutrition and Feed Science of Qinghai Province,Qinghai Plateau Yak Research Center;Academy of Animal Science and Veterinary Medicine of Qinghai University, Xining 810016)

机构地区：[1]省部共建三江源生态与高原农牧业国家重点实验室,高原放牧家畜动物营养与饲料科学重点实验室,青海省高原牦牛研究开发中心 [2]青海大学畜牧兽医科学院,西宁810016

出　　处：《青海畜牧兽医杂志》2020年第3期8-11,共4页Chinese Qinghai Journal of Animal and Veterinary Sciences

基　　金：青海省重点实验室专项(2013-Z-Y03)。

摘　　要：生长激素受体基因是泌乳性状重要候选基因,本试验对牦牛GHR基因exon 5片段进行了SNP检测,该结果表明牦牛GHR基因exon 5含SNP多态位点1个,第82位T,形成C/C和C/T两种基因型,且该SNP为非同义cSNP,碱基C/T的转换导致了编码氨基酸精氨酸/半胱氨酸的改变。The growth hormone receptor gene(GHR)is an important candidate gene for lactation traits,and the study of SNP polymorphism of GHR gene in yaks is an important basis for performance marker-assisted breeding of yak milk in the next step.In this study,the SNP of exon 5 fragment of the yak GHR gene was detected.The results showed that the yak GHR gene exon 5 contained one SNP polymorphic site at the 82nd T,forming two genotypes of C/C and C/T.The SNP was non-synonymous with cSNP,and the conversion of base C/T led to the change of the coding amino acid arginine/cysteine.

关 键 词：牦牛 GHR exon5 SNP 多态性 

分 类 号：S823.85[农业科学—畜牧学]