通督温阳灸治疗癌症化疗患者白细胞减少症临床研究  

Clinical Study on Governor Vessel-Unblocking and Yang-Warming Moxibustion for Patients with Leukopenia After Chemotherapy for Cancer

作　　者：荫晴[1] 马淑芳[1] 赵艳丽 李想[1] 王艳 YIN Qing;MA Shufang;ZHAO Yanli;LI Xiang;WANG Yan

机构地区：[1]河南省中医药研究院附属医院,河南郑州450000

出　　处：《新中医》2020年第11期176-178,共3页New Chinese Medicine

基　　金：河南省中医药科学研究专项课题(2018ZY2031)。

摘　　要：目的:观察通督温阳灸治疗癌症化疗患者白细胞减少的效果及对患者生活质量的影响。方法:将89例化疗后出现白细胞减少症患者随机分为2组,对照组44例给予重组人粒细胞巨噬细胞刺激因子、升白汤治疗及及常规护理干预,观察组45例在对照组的基础上加用通督温阳灸治疗;观察2组临床疗效、卡氏评分(KPS)、白细胞计数和治疗时间。结果:显效率观察组为95.56%,对照组为38.64%,2组比较,差异有统计学意义(P<0.05)。治疗7 d、14 d,2组患者白细胞计数均较治疗前明显升高(P<0.05);且观察组白细胞计数高于对照组(P<0.05)。治疗7 d、14 d,观察组KPS评分均较治疗前明显升高(P<0.05),且明显高于对照组(P<0.05)。治疗7 d,对照组KPS评分较治疗前升高,但差异无统计学意义(P>0.05);治疗14 d,对照组KPS评分明显高于治疗前(P<0.05)。结论:在常规治疗及护理干预的基础上,通督温阳灸治疗化疗后白细胞减少症,可有效提升患者白细胞计数,改善患者生活质量,临床疗效肯定。Objective:To observe the therapy of governor vessel-unblocking and yang-warming moxibustion for patients with leukopenia after chemotherapy for cancer and its effect on the quality of life. Methods:A total of 89 cases of patients with leukopenia after chemotherapy were divided into two groups randomly,44 and 45 cases in each group respectively. The control group was given recombinant human granulocyte-macrophage colony stimulating factor,Shengbai tang and routine nursing intervention, and the observation group was additionally given governor vessel-unblocking and yang-warming moxibustion. The clinical effect,the scores of Karnofsky Performance Status(KPS),white blood cell count and the treatment time in both groups were observed. Results:The obvious effective rate was 95.56% in the observation group and 38.64% in the control group,the difference being significant(P<0.05). At the 7 thand 14 thdays of treatment,the white blood cell counts in both groups were significantly higher than those before treatment(P<0.05);the white blood cell count in the observation group was higher than that in the control group(P<0.05). At the 7 thand 14 thdays of treatment, the scores of KPS in the observation group were significantly higher than those before treatment(P<0.05),and those in the control group(P<0.05). At the 7 thday of treatment, the score of KPS in the control group was higher than that before treatment, but there was no significance in the difference(P>0.05);at the 14 thday of treatment,the score of KPS in the control group was significantly higher than that before treatment(P<0.05). Conclusion:Based on routine treatment and nursing intervention,the therapy of governor vessel-unblocking and yang-warming for patients with leukopenia after chemotherapy, can effectively promote white blood cell counts of patients and improve their quality of life,with significant clinical effect.

关 键 词：白细胞减少症 化疗 重组人粒细胞巨噬细胞刺激因子 升白汤 通督温阳灸 

分 类 号：R557.1[医药卫生—血液循环系统疾病] R246.5[医药卫生—内科学]