四川省可疑帕金森病人群相关危险因素研究  

Study on Risk Factors of Suspected Parkinson’s Disease in Sichuan Province

作　　者：何君[1] 马霞 郭红菊[3] 常晓宇 王卓[1] 何予晋 邓颖[1] HE Jun;MA Xia;GUO Hongjun;CHANG Xiaoyu;WANG Zhuo;HE Yujin;DENG Ying(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China;Ji’nan Center for Disease Control and Prevention,Ji’nan 250023,Shangdong Province,China;Mianyang Center for Disease Control and Prevention,Mianyang 621000,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心,成都610041 [2]济南市疾病预防防控中心,济南250000 [3]绵阳市疾病预防控制中心,四川绵阳621000

出　　处：《预防医学情报杂志》2020年第6期683-689,695,共8页Journal of Preventive Medicine Information

摘　　要：目的探讨四川省可疑帕金森病(Parkinson’s disease,PD)人群相关危险因素。方法 2015年对绵阳地区≥60岁且居住一年以上的常住人口进行流行病学调查,采用简易帕金森病症状清单量表(The Parkinson’s disease symptom inventory,PDSI)进行可疑PD的筛查,再进行单因素及多因素非条件Logistic回归分析。结果筛查出可疑PD 1 024人,可疑PD检出率为25.45%(1 024/4 024)。单因素分析显示:年龄、文化程度、喝茶、体育锻炼、玩牌、上网、高血压、脑卒中、甘油三酯中的TG、HDL-C和LDL-C与可疑PD之间密切相关(P均<0.05);多因素非条件Logistic回归分析显示:年龄、高血压、脑卒中和HDL-C增加可疑PD发病风险(P均<0.05),文化程度、喝茶、体育锻炼、玩牌、上网、TG和LDL-C降低可疑PD发病风险(P均<0.05)。结论年龄、高血压、脑卒中和HDL-C是可疑PD的危险因素,文化程度、喝茶、体育锻炼、玩牌、上网、TG和LDL-C是保护因素。Objective To investigate the risk factors of suspicious Parkinson's disease in Mianyang.Methods The residents aged more than 60-year-old who lived in Mianyang for more than one year in 2015 were surveyed.The Parkinson's disease symptom inventory(PDSI)was used to screen for suspicious PD.Then,univariate and multivariate non-conditional Logistic regression analysis was performed.Results A total of 1024 people was found to have suspicious PD,and the prevalence rate of suspicious PD was 25.45%(1024/4024).Univariate Logistic regression analysis showed that age,education level,tea drinking,physical exercise,playing cards,Internet surfing,hypertension,stroke,TG,HDL-C and LDL-C in triglyceride were closely correlated with suspicious PD(P<0.05).Multivariate Logistic regression analysis showed that age,hypertension,stroke and HDL-C was associated with increased risk of suspicious PD(P<0.05).Whereas education level,tea drinking,physical exercise,playing cards,Internet surfing,TG and LDL-C were associated with decreased risk of suspicious PD(P<0.05).Conclusion Age,hypertension,stroke and HDL-C are the risk factors of suspicious PD.Education,tea drinking,physical exercise,playing card,Internet surfing,TG and LDL-C are the protective factors of suspicious PD.

关 键 词：PARKINSON病 可疑人群 危险因素 绵阳 

分 类 号：R181.3[医药卫生—流行病学]