临床药师参与耐碳青霉烯大肠埃希菌并耐甲氧西林表皮葡萄球菌感染患儿的药学监护  

Pharmaceutical Care for One Child Infected with Carbapene-Resistant Escherichia Coli and Meticillin Resistant Staphylococcus Aureus by Clinical Pharmacists

作　　者：方圆[1] 刘秀梅[1] 郭倩倩[1] 苑立博 Fang Yuan;Liu Xiumei;Guo Qianqian;Yuan Libo(People’s Hospital of Zhengzhou,Henan Zhengzhou 450003,China;Henan University of Technology,Henan Zhengzhou 450001,China)

机构地区：[1]郑州人民医院,河南郑州450003 [2]河南工业大学化学化工与环境学院,河南郑州450001

出　　处：《儿科药学杂志》2020年第7期34-37,共4页Journal of Pediatric Pharmacy

基　　金：国家自然科学基金青年科学基金项目,编号21708005。

摘　　要：目的:探讨临床药师在重症感染患儿抗感染治疗中的作用。方法:临床药师参与1例耐碳青霉烯类大肠埃希菌(CRE)并耐甲氧西林表皮葡萄球菌(MRSE)感染患儿的药学监护,协助医师调整、制定药物治疗方案。结果:临床药师应用专业知识,结合患儿的生理病理情况,利用药动学/药效学(PK/PD)参数优化抗感染治疗方案,患儿感染指标明显好转,病情稳定出院。结论:临床药师可以PK/PD角度作为切入点,将药学理论与临床实践相结合,协助医师制定有效的用药方案,成为治疗团队的重要组成部分。Objective:To investigate the role of clinical pharmacists in anti-infection therapy for children with severe infection.Methods:The clinical pharmacists participated into the pharmaceutical care for one child infected with carbapene-resistant Escherichia coli(CRE)and meticillin resistant Staphylococcus aureus(MRSE),and assisted the clinicians to adjust and formulate medication regimens.Results:The clinical pharmacists applied professional knowledge,combined with the physiological and pathological conditions of children,and used pharmacokinetics/pharmacokinetics(PK/PD)parameters to optimize the anti-infection treatment regimens.The infection indexes of the child were significantly improved,and the child was discharged steadily.Conclusion:The clinical pharmacists can take the PK/PD parameters as an entry point to integrate pharmacy theory with clinical practice,assist the clinicians in developing the effective medication regimen,and become an important part of the therapeutic team.

关 键 词：耐碳青霉烯类大肠埃希菌 耐甲氧西林表皮葡萄球菌 感染 药学监护 

分 类 号：R725.1[医药卫生—儿科]