冠脉血管内超声指导下对冠脉重度钙化病变介入治疗的临床研究  

Clinical study of coronary intravascular ultrasound imaging guide in the interventional therapy of severe calcification lesion

作　　者：苏永才[1] 张小乐[1] 邓斌[1] 苏良献[1] SU Yong-cai;ZHANG Xiao-le;DENG Bin;SU Liang-xian(Department of Cardiology,the First People′s Hospital of Zhaoqing City in Guangdong Province,Zhaoqing526021,China)

机构地区：[1]广东省肇庆市第一人民医院心内科,广东肇庆526021

出　　处：《中国当代医药》2020年第18期38-41,共4页China Modern Medicine

基　　金：广东省肇庆市科技局科技创新指导类项目(201504030812)。

摘　　要：目的 研究冠脉血管内超声(IVUS)对重度钙化病变介入治疗指导的有效性和安全性.方法 选取2016年1月~2019年1月在我院诊治的99例重度钙化病变且需行冠脉介入治疗的患者,按照冠脉介入治疗术中是否使用IVUS分为IVUS显像组(IVUS组,46例)和常规冠脉介入治疗组(常规组,53例).IVUS组患者行冠脉介入诊治术中使用IVUS处理,而常规组患者在冠脉介入诊治术中未使用IVUS.观察比较两组患者手术的支架植入成功率、术中和术后住院期间并发症发生率、住院期间及术后1年的临床主要不良心脏事件的随访结果.结果 IVUS组的支架植入成功率高于常规组,差异有统计学意义(P<0.05);两组术中和术后住院期间的并发症发生率比较,差异均无统计学意义(P>0.05).随访结果显示,IVUS组术后1年的临床主要不良心脏事件中心绞痛及心力衰竭发生率低于常规组,差异有统计学意义(P<0.05).结论 IVUS能提高冠脉重度钙化病变介入治疗的支架植入成功率,降低术后1年临床主要不良心脏事件的发生率.IVUS对冠脉重度钙化病变介入治疗具有临床指导意义.Objective To study the effectiveness and safety of coronary intravascular ultrasound(IVUS)imaging guide in the interventional therapy of severe calcification.Methods From January 2016 to January 2019,99 patients with severe calcification treated in our hospital and requiring coronary intervention were selected as the research objects,and they were divided into the coronary IVUS imaging group(the IVUS group,46 cases)and the routine coronary intervention group(the routine group,53 cases)according to whether to use IVUS during coronary intervention.IVUS was used in the IVUS group,IVUS was not used in the routine group.The success rate of stent implantation,the incidence of complications during operation and hospitalization after operation,and the follow-up results of major adverse cardiac events during hospitalization and after operation at one year were observed and compared between the two groups.Results The success rate of stent implantation in the IVUS group was higher than that in the routine group,and the difference was statistically significant(P<0.05).There was no significant difference between the two groups in the incidence of complications during operation and hospitalization after operation(P>0.05).The follow-up results showed that the incidence of central colic and heart failure in the IVUS group after operation at one year were significantly lower than those in the routine group,and the differences were statistically significant(P<0.05).Conclusion IVUS can improve the success rate of stent implantation and reduce the incidence of major clinical adverse cardiac events one year after operation,which has clinical significance in the interventional treatment of severe calcification of coronary artery.

关 键 词：冠脉血管内超声 冠心病 冠状动脉内旋磨术 钙化 介入治疗 

分 类 号：R445.1[医药卫生—影像医学与核医学]