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作 者:任秀华[1] 祁星星 左琴 汤杰 刘东[1] REN Xiuhua;QI Xingxing;ZUO Qin;TANG Jie;LIU Dong(Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)
机构地区:[1]华中科技大学同济医学院附属同济医院药学部,武汉430030
出 处:《医药导报》2020年第7期926-930,共5页Herald of Medicine
基 金:“重大新药创制”科技重大专项(2017ZX09304022);中央高校基本科研业务费专项资金(2020kfyXGYJ050)。
摘 要:目的回顾性分析光谷方舱医院新型冠状病毒肺炎(COVID-19)患者资料,了解方舱医院COVID-19患者用药合理性。方法收集光谷方舱医院813例COVID-19患者信息,采用SPSS 25.0版统计软件分析患者性别、年龄、临床诊断、用药、住院时间、转归等。结果813例COVID-19患者中,男418例(51.41%),女395例(48.59%);有基础疾病者144例(17.71%),COVID-19疑似患者505例(62.12%),COVID-19确诊患者308例(37.88%)。不同年龄组性别、合并基础疾病、临床分型差异有统计学意义(P<0.05);阿比多尔、连花清瘟胶囊在光谷方舱医院应用广泛,对治疗COVID-19发挥了一定作用;阿比多尔、连花清瘟胶囊、清肺排毒汤、莫西沙星使用频数分别为341,339,232,227例;不同年龄组应用连花清瘟胶囊、强力枇杷露、莫西沙星差异有统计学意义(P<0.05),不同年龄患者转归差异有统计学意义(P<0.05)。结论光谷方舱医院不同年龄患者性别组成、基础疾病、COVID-19临床分型、转归均差异有统计学意义。患者用药基本合理,利巴韦林和盐酸莫西沙星的合理使用需加强监护。Objective To retrospectively analyze the data related to the treatment of coronavirus disease 2019(COVID-19)in the square cabin hospital,and to explore the rationality of medication treatment.Methods A total of 813 patients with COVID-19 in the square cabin hospital were collected and analyzed with SPSS 25.0 software for statistical description and statistical analysis of the patients'gender,age,clinical diagnosis,medication,hospitalization days,outcomes,etc.Results Of the 813 COVID-19 patients,there were 418(51.41%)male,395(48.59%)female,and 144(17.71%)patients with underlying diseases.There were 505(62.12%)suspected cases and 308(37.88%)confirmed cases.The frequency of gender,underlying disease,and clinical classification had significant differences among different age groups(P<0.05).Arbidol and Lianhua Qingwen capsules were widely used in the square cabin hospital,which had played a certain role in the treatment of COVID-19 patients.The frequency of arbidol,Lianhua Qingwen capsule,Qingfei Paidu decoction,and moxifloxacin were 341,339,232,and 227,respectively.In addition,the application of Lianhua Qingwen capsule,Qiangli Loquat Dew,and moxifloxacin among different age groups were significantly different(P<0.05).Moreover,the outcomes of patients among different age groups were also significantly different(P<0.05).Conclusion In the square cabin hospital,there were differences in gender,underlying diseases,clinical types and outcomes of patients with different age groups.The medications were basically reasonable,but the possible unreasonable use of ribavirin and moxifloxacin should be supervised.
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