Efficacy of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia and its effect on serum hormone levels  

经皮穴位电刺激干预更年期失眠的疗效及对血清激素水平的影响

作　　者：Wang Min-chao Lin Li-hong 王敏超;林丽红(Lishui Second People's Hospital,Zhejiang 323000,China)

机构地区：[1]Lishui Second People's Hospital,Zhejiang 323000,China

出　　处：《Journal of Acupuncture and Tuina Science》2020年第3期197-202,共6页针灸推拿医学（英文版）

基　　金：浙江省丽水市科技计划项目,No.2017GYX28.

摘　　要：Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each group.The patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication treatment.The treatment for both groups lasted for 4 weeks.Before and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were measured.The therapeutic efficacy was evaluated after treatment.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);in the control group,the improvement of PSQI score was significant(P<0.05),while the change of modified Kupperman score was insignificant(P>0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P<0.05),and there were significant differences between the observation group and the control group in PSQI and Kupperman scores(both P<0.05).After treatment,the serum E2 and FSH levels in the control group were not statistically different from those before treatment(both P>0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.目的:探讨经皮穴位电刺激(TEAS)干预更年期失眠的疗效及作用机制.方法:将80例更年期失眠患者随机分为对照组和观察组,每组40例.对照组予常规西药治疗,观察组在对照组常规西药治疗基础上加用TEAS治疗.共治疗4周.治疗前后进行匹兹堡睡眠质量指数(PSQI)和改良Kupperman量表评分,并测定患者血清雌二醇(E2)及卵泡刺激素(FSH)水平.于治疗结束后进行疗效评价.结果:治疗后,观察组总有效率明显高于对照组(P<0.05);对照组PSQI评分较治疗前改善(P<0.05),改良Kupperman评分变化无统计学意义(P>0.05);观察组PSQI及改良Kupperman评分均有明显改善(均P<0.05),且与对照组有统计学差异(均P<0.05).治疗后,对照组患者血清E2及FSH水平与治疗前无统计学差异(均P>0.05);观察组患者血清E2水平明显升高(P<0.05),FSH水平降低(P<0.05),且组间有统计学差异(均P<0.05).结论:常规西药治疗基础上加用TEAS治疗更年期失眠疗效确切,可显著改善患者失眠症状及更年期症状,这可能与其调节患者血清E2和FSH水平有关.

关 键 词：Acupoint Therapy Transcutaneous Electric Nerve Stimulation INSOMNIA CLIMACTERIC PERIMENOPAUSE HORMONES WOMEN 

分 类 号：R245.9[医药卫生—针灸推拿学]