银翘散不同煎煮时间治疗时行感冒邪在肺卫证74例疗效观察  

Clinical Observation on Yinqiao Powder(银翘散)in Different Decocting Time for Treating 74 Cases of Influenza with Pathogen in Lung-Defense Syndrome

作　　者：霍炳杰[1] 常靓 张风宾[1] 张霞 HUO Bingjie;CHANG Liang;ZHANG Fengbin;ZHANG Xia(The Fourth Hospital of Hebei Medical University,Shijiazhuang,050011;Hebei University of Chinese Medicine)

机构地区：[1]河北医科大学第四医院,050011 [2]河北中医学院

出　　处：《中医杂志》2020年第12期1065-1068,共4页Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81202679);河北省中医药管理局科研计划(2016053)。

摘　　要：目的观察银翘散在不同煎煮时间下对时行感冒邪在肺卫证患者的疗效。方法将110例时行感冒邪在肺卫证患者随机分为银翘散煮沸6min组38例、银翘散煮沸12min组36例和对照组36例。银翘散煮沸6min组、12min组分别服用煮沸6min、12min的银翘散,每4h服用1次,日3次,夜1次,对照组服用磷酸奥司他韦胶囊,每次75mg,日2次,疗程均为5d。比较各组患者退热起效时间、体温复常时间,治疗前后中医症状积分变化,并进行疾病疗效和中医证候疗效的判定。结果银翘散煮沸6min组、12min组患者退热起效时间和体温复常时间明显短于对照组,且银翘散煮沸6min组明显短于银翘散煮沸12min组(P<0.05)。治疗后,各组中医症状积分均较本组治疗前明显降低(P<0.05),且银翘散煮沸6min组和12min组中医症状积分低于对照组(P<0.05),同时治疗后银翘散煮沸6min组中医症状积分低于银翘散煮沸12min组(P<0.05)。银翘散煮沸6min组、12min组的疾病疗效、中医证候疗效均显著高于对照组(P<0.05),且银翘散煮沸6min组优于银翘散煮沸12min组(P<0.05)。结论银翘散煮沸后6min对时行感冒邪在肺卫证患者在体温变化、中医症状、疾病疗效及证候疗效方面均优于煮沸后12min。Objective To observe clinical effects of Yinqiao Powder(银翘散)in different decocting time on the patients of influenza with pathogen in lung-defense syndrome.Methods A total of 110 cases of patients of influenza with pathogen in lung-defense syndrome were randomly divided into 6-minute group of 38 cases,12-minute group of 36 cases and control group of 36 cases.The 6-minute group and 12-minute group were given Yinqiao Powder boiling for 6 minutes and 12 minutes respectively,once every 4 hours,3 times during day-time and once at night.The control group was given oseltamivir phosphate capsule,75 mg each time,twice a day.The treatment course was 5 days for all groups.The onset time and recovery time of body temperature of each group,and the changes of traditional Chinese medicine(TCM)symptom scores before and after treatment were compared.Results The start time of fever reduction and recovery time of body temperature of patients in the 6-minute group and 12-minute group were significantly shorter than those in the control group,and changes in the 6-minute group was more significant than the 12-minute group(P<0.05).After treatment,the scores of symptoms in all groups were significantly lower than those before treatment(P<0.05),the scores of symptoms in 6-minute group and 12-minute group were lower than those in the control group(P<0.05),and the scores of symptoms in 6-minute group were lower than those in the 12-minute group(P<0.05).The therapeutic effects of diseases and syndromes of 6-minute group and 12-minute group were significantly supperior to that of the control group(P<0.05),and the therapeutic effects of the 6-minute group were significantly supperior to that of the 12-minute group(P<0.05).Conclusion Yinqiao Powder boiling for 6 minutes were better than 12 minutes after boiling for influenza in lung-defense syndrome in the temperature changes,symptoms of traditional Chinese medicine,disease efficacy and syndrome efficacy.

关 键 词：银翘散 煎煮时间 时行感冒 邪在肺卫证 

分 类 号：R285.6[医药卫生—中药学]