白芥子涂方治疗支气管哮喘疗效及对FEF25、FEF50、FEF75变化的研究  

Study on Control Effect and Changes of FEF25, FEF50 and FEF75 of Bronchial Asthma Patients Treated with Baijiezi Tufang

作　　者：黄霞飞[1] 胡强 申俊霞 田业 杨晓琴 HUANG Xiafei;HU Qiang;SHEN Junxia;TIAN Ye;YANG Xiaoqin(Department of Intemal Medicine,Panzhihua Third People's Hospital,Panzhihua 617000,Sichuan,China;Department of Respiration and Critical Care,The Affiliated Hospital of Panzhihua College,Panzhihua 617000,Sichuan,China;Department of Internal Medicine,The Fifth Peoples Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830011,China;Department of Respiratory Medicine,Suiyang County Peoples Hospital,Suiyang 563300,Guizhou,China)

机构地区：[1]攀枝花市第三人民医院内科,四川攀枝花617000 [2]攀枝花学院附属医院呼吸与危重症科,四川攀枝花617000 [3]新疆维吾尔自治区第五人民医院内科,新疆乌鲁木齐830011 [4]绥阳县人民医院呼吸内科,贵州绥阳563300

出　　处：《中华中医药学刊》2020年第5期45-47,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家科技支撑计划(2017BAI21B56)。

摘　　要：目的研究白芥子涂方对支气管哮喘患者的防治效果及用力呼出25%肺活量的呼气流量(FEF25)、用力呼出50%肺活量的呼气流量(FEF50)、用力呼出75%肺活量的呼气流量(FEF75)的变化。方法选择医院2016年9月—2017年8月收治的支气管哮喘患者206例纳入研究,按照随机数字表法均分为两组,对照组、观察组各103例,对照组在缓解期未接受任何防治干预,观察组在2017年三伏天期间接受白芥子涂方防治干预,随访一年观察两组患者的防治效果及FEF25、FEF50、FEF75的变化。结果观察组的哮喘发作次数显著少于对照组,哮喘症状评分显著低于对照组,且总有效率显著高于对照组,差异有统计学意义(P<0.05);干预前两组患者的FEF25、FEF50、FEF75比较差异均无统计学意义(P>0.05),干预后观察组的FEF25、FEF50、FEF75显著降低,且明显低于对照组,差异有统计学意义(P<0.05);以成人哮喘生存质量量表(AQLQ)评定两组患者的生活质量,干预前两组的AQLQ评分差异无统计学意义(P>0.05),干预后观察组AQLQ评分显著低于对照组,差异有统计学意义(P<0.05)。结论白芥子涂方对支气管哮喘患者的防治效果显著,能够改善患者的小气道功能,缓解哮喘发作状况,从而提高患者的生活质量。Objective To study the control effect and changes of forced expiratory flow at 25%of FVC exhaled(FEF25),forced expiratory flow at 50%of FVC exhaled(FEF50)and forced expiratory flow at 75%of FVC exhaled(FEF75)of bronchial asthma patients treated with Baijiezi Tufang.Methods Totally 206 patients with bronchial asthma in our hospital from September 2016 to August 2017 were selected in the study.The patients were divided into two groups according to the random number table method and each group had 103 cases.The control group did not receive any preventive intervention during the remission period and the observation group received the intervention of Baijiezi Tufang during dog-day of 2017 and was followed-up for one year.The control effect and changes of FEF25,FEF50 and FEF75 of two groups were observed.Results The number of asthma attacks in the observation group was significantly less than that of the control group.The asthma symptom score of the observation group was significantly lower than that of the control group,and the total effective rate was significantly higher than that of the control group.The differences were statistically significant(P<0.05).There were no significant differences in FEF25,FEF50 or FEF75 of two groups before intervention(P>0.05).The FEF25,FEF50 and FEF75 in the observation group were significantly lower after intervention,and they were significantly lower than those of the control group.The differences were statistically significant(P<0.05).The quality of life of two groups was assessed by the Asthma Quality of Life Questionnaire(AQLQ)and there was no significant difference in AQLQ scores between two groups before intervention(P>0.05).The AQLQ score of the observation group after intervention was significantly lower than that of the control group,and the differences were statistically significant(P<0.05).Conclusion Baijiezi Tufang has a significant control effect for bronchial asthma patients,and can improve the small airway function of patients,relieve asthma attacks and improve the qu

关 键 词：支气管哮喘 白芥子涂方 小气道功能 生活质量 

分 类 号：R562.25[医药卫生—呼吸系统]