艾滋病合并弓形虫脑炎临床诊疗的专家共识  

Expert Consensus on the Diagnosis and Treatment of Toxoplasmic Encephalitis in AIDS Patients

作　　者：“十三五”国家科技重大专项艾滋病机会性感染课题组 陈耀凯 吴昊 曾妍茗 李瑶 AIDS-Associated Opportunistic Infections Research Group of the National Science and Technology Major Project of China During the 13th Five-Year Plan Period

机构地区：[1]不详 [2]重庆市公共卫生医疗救治中心感染病科

出　　处：《西南大学学报（自然科学版）》2020年第7期38-48,共11页Journal of Southwest University(Natural Science Edition)

基　　金：“十三五”国家科技重大专项(2018ZX10302104).

摘　　要：弓形虫脑炎(toxoplasmic encephalitis,TE)是艾滋病(acquired immunodeficiency syndrome,AIDS)患者最常见的神经系统机会性感染之一,迄今仍是严重威胁艾滋病患者生命与健康的重要原因.艾滋病合并弓形虫脑炎(AIDS/TE)在流行病学、发病机制、临床特征、诊断与鉴别诊断、治疗和预防等方面均具有一定的特殊性,然而目前尚缺乏系统的指南性文献可供参考.该共识在综合现有文献与课题研究结果的基础上,就AIDS/TE的流行情况、发病机制、临床特征、诊断、防治等内容进行详细阐述,以期为该疾病临床诊疗提供参考.Toxoplasma encephalitis(TE)is a common opportunistic infection of the central nervous system of acquired immunodeficiency syndrome(AIDS)patients,and remains a significant threat to their health and life.Acquired immunodeficiency syndrome/toxoplasma encephalitis(AIDS/TE)is disease-specific in epidemiology,pathogenesis,clinical manifestations,diagnosis and differential diagnosis,treatment,and prevention.However,no systematic guideline for AIDS/TE is available for reference in current literature.This consensus document presents a detailed discussion about the epidemiology,pathogenesis,clinical manifestations,diagnosis,treatment,and prevention of AIDS/TE based on current data derived from the existing literature and research results so as to provide a reference for the clinical diagnosis and treatment of AIDS/TE.

关 键 词：艾滋病 弓形虫脑炎 诊断 治疗 共识 

分 类 号：R512.91[医药卫生—内科学] R512.3[医药卫生—临床医学]