2014-2018年深圳市体检人群流感抗体水平监测  

Surveillance of antibody level of influenza among physical examination population of Shenzhen City from 2014 to 2018

作　　者：连宪强 刘坚基 叶裕正 王文祥 杨粤 朱文杰 黄妙芬 LIAN Xian-qiang;LIU Jian-ji;YE Yu-zheng;WANG Wen-xiang;YANG Yue;ZHU Wen-jie;HUANG Miao-fen(Dapeng New District Center for Public Health Management and Service,Shenzhen,Guangdong 518116,China)

机构地区：[1]深圳市大鹏新区公共卫生管理服务中心,广东深圳518116

出　　处：《上海预防医学》2020年第4期325-328,共4页Shanghai Journal of Preventive Medicine

摘　　要：【目的】监测深圳市大鹏新区一般人群流行性感冒(流感)抗体水平,为流感疫情的预防和控制提供科学依据。【方法】2014—2018年共10次采用血凝集抑制试验对采集的1350份人群血清进行抗体检测。【结果】2014—2018年,H3N2的抗体阳性率为60%以上,H1N1、H3N2、BV和BY流感毒株的抗体阳性率分别为50.0%、85.6%、35.4%和45.6%,抗体几何平均滴度(GMT)分别为8.2、81.5、3.9、6.4。流感抗体效价1∶160和1∶320主要分布于H3N2型流感中。BV型和BY型流感毒株抗体水平在0~岁年龄组中阳性率分别为29.0%和30.4%。【结论】大鹏新区应继续加强一般人群血清中流感抗体水平监测,实时了解流感毒株流行发展趋势,预防控制流感疫情暴发。[Objective]To provide the basis for influenza epidemic prevention and control by monitoring the antibody level of influenza among the general population in Dapeng New District of Shenzhen City.[Methods]A total of 1350 serum samples of people were collected ten times from 2014 to 2018,and the antibody level was tested by hemagglutination-inhibition test.[Results]During 2014-2018 years,only the positive rate of antibody to H3N2 was above 60%.The positive rates of H1N1,H3N2,BV and BY were 50.0%,85.6%,35.4%and 45.6%,respectively,and the geometric mean titers(GMT)of antibody were 8.2,81.5,3.9 and 6.4,respectively.Influenza antibody titers of 1∶160 and 1∶320 were mainly distributed in influenza H3N2.The antibody level of BV and BY in age group 0~4 years was 29.0%and 30.4%separately.[Conclusion]It is imperative to enhance the surveillance of antibody level of influenza among general population in Dapeng New District,to investigate the epidemic development trend of influenza constantly,and to prevent and control the outbreak of influenza epidemics.

关 键 词：流感 血凝抑制试验 抗体水平 疫情控制 

分 类 号：R183.3[医药卫生—流行病学]