血清胆红素、血尿酸水平与冠状动脉狭窄程度的相关性分析  

Analysis on the Correlations of Serum Bilirubin and Blood Uric Acid Levels with Degree of Coronary Artery Stenosis

作　　者：林佑妮 杨敏[1] 蓝新平[1] LIN Youni;YANG Min;LAN Xinping(4th Department of Cardiovascularology,Meizhou People's Hospital,Meizhou 514031,China)

机构地区：[1]梅州市人民医院心血管内四科,广东梅州514031

出　　处：《临床医学工程》2020年第8期1061-1062,共2页Clinical Medicine & Engineering

摘　　要：目的分析血清胆红素、血尿酸水平与冠状动脉狭窄程度的相关性,评价其临床诊断价值。方法回顾性分析我院2017年7月至2019年3月期间收治的93例冠心病患者的临床资料,所有患者均接受冠状动脉造影检查,根据造影结果判断冠状动脉狭窄程度并进行分组。记录各组的血清胆红素及血尿酸水平,分析二者与冠脉动脉狭窄程度的相关性。结果 93例冠心病患者的冠脉造影结果显示:冠脉动脉轻度狭窄34例(轻度组),中度狭窄35例(中度组),重度狭窄24例(重度组)。三组的血尿酸水平比较,重度组>中度组>轻度组,差异有统计学意义(P <0.05);三组的总胆红素水平比较,重度组<中度组<轻度组,差异有统计学意义(P <0.05)。血尿酸水平与冠状动脉狭窄程度呈正相关(r=0.566, P <0.05),总胆红素水平与冠状动脉狭窄程度呈负相关(r=-0.957, P <0.05)。结论冠心病患者的血清胆红素、血尿酸水平与冠状动脉狭窄程度密切相关,血清胆红素水平越低、血尿酸水平越高,提示冠状动脉狭窄程度越严重,二者可用于冠心病患者冠状动脉狭窄程度的判断。Objective To analyze the correlations of serum bilirubin and uric acid levels with degree of coronary artery stenosis,and to evaluate the clinical diagnostic value of serum bilirubin and uric acid.Methods The clinical data of 93 patients with coronary heart disease admitted to our hospital from July 2017 to March 2019 were retrospectively analyzed.All patients underwent coronary angiography to determine the degree of coronary artery stenosis,and were grouped according to the angiography results.The serum bilirubin and blood uric acid levels in each group were recorded,and the correlations between two indicators and the degree of coronary artery stenosis were analyzed.Results The results of coronary angiography showed that there were 34 cases of mild coronary artery stenosis(mild group),35 cases of moderate stenosis(moderate group),and 24 cases of severe stenosis(severe group).The comparison showed that serum uric acid levels were fromhigh to lowin severe group,moderate group and mild group,with statistically significant differences(P<0.05).The comparison showed that total bilirubin levels were from low to high in severe group,moderate group and mild group,with statistically significant differences(P<0.05).Serum uric acid level was positively correlated with the degree of coronary artery stenosis(r=0.566,P<0.05),and total bilirubin level was negatively correlated with the degree of coronary artery stenosis(r=-0.957,P<0.05).Conclusions Serum bilirubin and uric acid levels in patients with coronary heart disease are closely related to the degree of coronary artery stenosis.The lower the serum bilirubin level and the higher the blood uric acid level are,the more serious the degree of coronary artery stenosis is.Serum bilirubin and uric acid can be used to judge the degree of coronary artery stenosis in patients with coronary heart disease.

关 键 词：冠心病 胆红素 血尿酸 冠状动脉狭窄程度 

分 类 号：R541.4[医药卫生—心血管疾病]