一种新型次氯酸消毒剂对纤维支气管镜的消毒效果  

Disinfection effect of a new type of hypochlorous acid disinfectant on fiberbronchoscopes

作　　者：钱麟 史庆丰 许华[1] 王春灵[1,3] QIAN Lin;SHI Qing-feng;XU Hua;WANG Chun-ling(Central Sterile Supply Department,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China;Department of Healthcare-associated Infection Management,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China;Department of Operating Room,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院消毒供应中心,上海200032 [2]复旦大学附属中山医院感染管理科,上海200032 [3]复旦大学附属中山医院手术室,上海200032

出　　处：《中国感染控制杂志》2020年第7期662-665,共4页Chinese Journal of Infection Control

摘　　要：目的评价一种新型次氯酸消毒剂对纤维支气管镜的消毒效果。方法60条使用后的纤维支气管镜严格按照操作规范流程清洗后,使用次氯酸消毒剂分别进行机洗消毒3、5 min,采用ATP生物荧光检测法和滤膜法对纤维支气管镜的外表面和内腔表面进行消毒效果的监测和评价,并与未清洗前、酶洗前进行比较。结果30条纤维支气管镜使用后未清洗前,内镜外表面RLU中位值为911.5,合格率为16.7%;酶洗后机洗前,内镜外表面RLU中位值为234.0,合格率为43.3%。每组30条纤维支气管镜经消毒剂分别浸泡消毒5、3 min后,气管镜外表面RLU中位值分别为25.0、23.5,合格率均为100.0%。连续使用7 d后,有效浓度仍维持在80 mg/L以上。结论该新型次氯酸消毒剂作用3 min即可对纤维支气管镜产生良好的消毒效果,提高了工作效率,并具备良好的安全性和稳定性。Objective To evaluate the disinfection effect of a new hypochlorous acid disinfectant on fiberbronchoscopes.Methods 60 used fiberbronchoscopes were strictly cleaned in accordance with the operation procedures,then fiberbronchoscopes were performed machine washing and disinfection with hypochlorous acid disinfectant for 3 and 5 minute respectively.ATP bioluminescence assay and membrane filtration method were used to monitor and evaluate the disinfection effect on the outer and inner surface of fiberbronchoscopes,result was compared with before cleaning and enzyme washing.Results The median value of relative light unit(RLU)on the outer surface of 30 used fiberbronchoscopes before cleaning was 911.5,qualified rate was 16.7%;after enzyme washing but before machine washing,the median value of RLU on the outer surface of fiberbronchoscopes was 234.0,qualified rate was 43.3%.After each group of 30 fiberbronchoscopes were immersed in disinfectant for 5 and 3 minutes respectively,median values of RLU of the outer surface of fiberbronchoscopes were 25.0 and 23.5 respectively,qualified rates were both 100.0%.Concentration of hypochlorous acid disinfectant could maintain at effective concentration(≥80 mg/L)after continuous use for 7 days.Conclusion The new hypochlorous acid disinfectant can achieve good disinfection effect on fiberbronchoscopes for 3-minute contact time,and improve work efficiency with good safety and stability.

关 键 词：次氯酸消毒剂 纤维支气管镜 滤膜法 ATP生物荧光法 

分 类 号：R187[医药卫生—流行病学]