鱼类体色相关功能基因的研究进展  

Research progress on color-related genes of fish

作　　者：孟超 徐皓 黄超 李明明 宫晓婷 田光辉 孙钰 李宇飞 李慧 苏延友 Meng Chao;Xu Hao;Huang Chao;Li Mingming;Gong Xiaoting;Tian Guanghui;Su Yu;Li Yufei;Li Hui;Su Yanyou(Collegeof Life Sciences,Shandong First Medical University&Shandong Academy of Medical Sciences,Taian 271016,China;Collegeof Pharmacy,Shandong First Medical University&Shandong Academy of Medical Sciences,Taian 271016,China)

机构地区：[1]山东第一医科大学(山东省医学科学院)生命科学学院,山东泰安271016 [2]山东第一医科大学(山东省医学科学院)药学院,山东泰安271016

出　　处：《湖南文理学院学报（自然科学版）》2020年第3期30-35,共6页Journal of Hunan University of Arts and Science(Science and Technology)

基　　金：国家级大学生创新创业计划项目(201510439009,20161043927);山东省医药卫生科技发展计划项目(2018WS-139);泰安市科技局项目(2018NS0098)。

摘　　要：鱼类表皮色素形成复杂,涉及一系列基因表达调控、基因编码酶催化及细胞因子等参与。为了解鱼类体色形成的相关机制,本文综述了色素合成通路中重要色素——黑色素形成的分子机制,并对鱼类体色相关基因中的酪氨酸酶相关蛋白1基因(tyrosinase-related protein gene 1,TYR1)、性别决定区基因(sex determining region Y-box 10,SOX10)、多巴素异构酶基因(dopachrome tautomerase,DCT)、黑皮质素受体-1基因(melanocortin 1 receptor,MC1R)和鼠灰色基因(Agouti)的研究进展概括。对于鱼类遗传、系统发育及分子进化等领域的研究具有重要意义,为体色形成机制提供理论参考和借鉴,并展望了今后对鱼类体色形成机制研究的新方向。The formation mechanism of body color is of great significance to the research of fish genetics,phylogeny and molecular evolution.In order to understand the mechanism of fish body color formation,the paper reviews important pigments in synthesis pathway-the formation mechanism of melanin and the research progress of TYRP1,SOX10,DCT,MC1R and Agouti,which is of great significance to the research of fish genetics,phylogeny and molecular evolution.The theoretical reference for the formation mechanism of body color in fish is demonstrated.It has also been proposed that the new research direction of fish body formation mechanism in the future.

关 键 词：鱼 体色基因 TYRP1 SOX10 DCT MC1R AGOUTI 

分 类 号：Q953[生物学—动物学]