甲状腺疾病术中冰冻切片及石蜡切片病理诊断结果的对照分析  

Comparative analysis of pathological findings of intraoperative frozen sections and paraffin sections in thyroid disease

作　　者：袁继华[1] Yuan Jihua(The People's Hospital of Shimen County,Changde City,Hunan Province,Hunan Shimen 415300)

机构地区：[1]湖南省常德市石门县人民医院,湖南石门415300

出　　处：《中国社区医师》2020年第19期126-127,共2页Chinese Community Doctors

摘　　要：目的:探讨甲状腺疾病术中冰冻切片及石蜡切片病理诊断的差异。方法:选取2018年7月-2019年11月手术治疗的甲状腺疾病患者426例,所有患者均于术中切取肉眼可见的甲状腺病变组织1~4块,选取灰白色硬质小结节的部位进行冰冻切片和石蜡切片病理诊断。结果:石蜡切片诊断为恶性病变182例,良性病变244例;而冰冻切片正确诊断405例,误诊10例,延迟诊断11例,诊断符合率为95.1%,误诊率为2.3%,延迟诊断率为2.6%。结论:冰冻切片诊断快速,是鉴别甲状腺良恶病变的有效方法,但受多种因素影响仍有一定误诊率及延迟诊断,故术后仍需进行石蜡切片病理诊断,以提高准确率。Objective:To investigate the differences of pathological diagnosis between intraoperative frozen sections and paraffin sections in thyroid disease.Methods:From July 2018 to November 2019,426 patients with thyroid disease who treated by surgery were selected,all the patients were cut 1 to 4 thyroid lesions which were visible to the naked eye during operation,the sites of gray-white hard nodules were selected for frozen sections and paraffin sections pathological diagnosis.Results:The paraffin sections were diagnosed with 182 cases of malignant lesions and 244 cases of benign lesions.The frozen sections were correctly diagnosed in 405 cases,10 cases of misdiagnosed,11 cases of delayed,the diagnostic coincidence rate was 95.1%,the misdiagnosis rate was 2.3%,the delayed diagnosis rate was 2.6%.Conclusion:The diagnosis of frozen sections is very fast,which is an effective method to identify the lesions of thyroid,however,due to many factors,there is still a certain rate of misdiagnosis and delayed diagnosis,so it is still necessary to carry out paraffin sections to improve the accuracy after operation.

关 键 词：甲状腺疾病 术中冰冻切片 石蜡切片 病理诊断 

分 类 号：R653[医药卫生—外科学]