黄体酮胶囊联合地屈孕酮片治疗先兆流产的疗效观察  

Clinical Observation of Progesterone Capsule Combined with Didrogesterone Tablets in the Treatment of Threatened Abortion

作　　者：徐阳 XU Yang(Shenyang Maternal and Infant Hospital,Shenyang 110011,China)

机构地区：[1]沈阳市妇婴医院,辽宁沈阳110011

出　　处：《中国医药指南》2020年第19期60-61,共2页Guide of China Medicine

摘　　要：目的分析探究黄体酮胶囊联合地屈孕酮片治疗先兆流产的疗效。方法本次将我院在2018年1月~12月收治的80例先兆流产患者视为研究的主对象,进一步以随机数字表法分成两个不同的组别,每组平均为40例;其中对照组患者给予黄体酮胶囊治疗,观察组患者给予黄体酮胶囊联合地屈孕酮片,对比两组用药效果及安全性。结果①观察组腰部疼痛、下腹部疼痛、阴道出血消除时间和对照组比较均显著更短,两组之间的数据存在明显统计学差异。②治疗前,两组孕酮水平无明显差异(P> 0.05);治疗后,观察组孕酮水平明显高于对照组,两组数据对比有显著性差异(P <0.05)。③观察组不良反应总发生率的7.50%,明显低于对照组的27.50%,两组数据对比有显著性差异(P <0.05),具备统计学意义。④在保胎成功率方面,观察组的97.50%显著要比对照组的82.50%高,两组之间的数据具备统计学研究的价值(P <0.05)。结论黄体酮胶囊联合地屈孕酮片治疗先兆流产,疗效显著,保胎成功率高,且不良反应轻微;因此,值得在临床实践中推广使用。Objective To analyze the effect of progesterone capsule combined with didrogesterone tablet in the treatment of threatened abortion.Methods 80 cases of threatened abortion patients admitted to our hospital from January to December 2018 were regarded as the main subjects of the study.They were further divided into two groups by random number table method,with an average of 40 cases in each group.The patients in the control group were treated with progesterone capsule,while those in the observation group were treated with progesterone capsule combined with didrogesterone tablet.The efficacy and safety of the two groups were compared.Results(1)The time of waist pain,lower abdominal pain,vaginal bleeding elimination in the observation group was significantly shorter than that in the control group,and there were significant statistical differences between the two groups.(2)Before treatment,there was no significant difference in progesterone level between the two groups(P>0.05);after treatment,the progesterone level in the observation group was significantly higher than that in the control group,and there was a significant difference between the two groups(P<0.05).(3)The total incidence of adverse reactions in the observation group was 7.50%,which was significantly lower than 27.50%in the control group.There was a significant difference between the two groups(P<0.05),with statistical significance.(4)In terms of the success rate of fetal protection,97.50%of the observation group was significantly higher than 82.50%of the control group,and the data between the two groups had the value of statistical research(P<0.05).Conclusion Progesterone capsule combined with Didrogesterone Tablet is effective in the treatment of threatened abortion,with high success rate of fetal protection and slight side effects.Therefore,it is worth popularizing in clinical practice.

关 键 词：黄体酮胶囊 地屈孕酮片 治疗 先兆流产 疗效 

分 类 号：R714.21[医药卫生—妇产科学]