小儿上呼吸道感染治疗中应用喜炎平注射液的临床价值  

Clinical Value of Application of Xiyanping Injection in the Treatment of Upper Respiratory Tract Infection in Children

作　　者：马琰 MA Yan(Department of Pharmacy,Shenyang Seventh People's Hospital,Shenyang 110003,China)

机构地区：[1]沈阳市第七人民医院药剂科,辽宁沈阳110003

出　　处：《中国医药指南》2020年第19期154-155,共2页Guide of China Medicine

摘　　要：目的分析小儿上呼吸道感染治疗中应用喜炎平注射液的临床价值。方法选取2016年3月至2019年12月本院收治的102例小儿上呼吸道感染患儿,根据不同治疗方案将其分成两组各51例,对照组采用利巴韦林注射液[10 mg/(kg·d),配以5%葡萄糖溶液250 mL,静脉滴注,qd]治疗,观察组在此基础上采用喜炎平注射液[5 mg/(kg·d),配以5%葡萄糖溶液250 mL,静脉滴注,qd]治疗,7 d后比较两组患儿的症状消失时间和临床疗效,统计不良反应发生情况。结果观察组患儿发热消失时间、咳嗽消失时间和鼻塞流涕消失时间明显短于对照组(P <0.05);观察组治疗有效率(96.08%)明显高于对照组(80.39%)(P <0.05);观察组不良反应发生率为(5.88%),对照组为(9.80%),两组不良反应发生率比较无明显差异(P> 0.05)。结论应用喜炎平注射液治疗小儿上呼吸道感染可有效缩短患儿症状消失时间,提升临床疗效,安全性可靠。Objective To analyze the clinical value of Xiyanping injection in the treatment of upper respiratory tract infection in children.Methods A total of 102 children with upper respiratory tract infection admitted to our hospital from March 2016 to December 2019 were enrolled in this study.According to different treatment protocols,51 patients were divided into two groups.The control group was treated with ribavirin injection[10 mg/(kg•d),with 250 mL of 5%glucose solution,intravenous drip,qd]treatment,the observation group on this basis using Xiyanping injection[5 mg/(kg•d),with 5%glucose solution 250 mL Intravenous infusion,qd]treatment,7 days after the two groups of children with symptom disappearance time and clinical efficacy,statistical adverse reactions occurred.Results The disappearance time,disappearance time of cough and disappearance of nasal obstruction were significantly shorter in the observation group than in the control group(P<0.05).The effective rate of treatment in the observation group(96.08%)was significantly higher than that in the control group(80.39%).P<0.05;the incidence of adverse reactions in the observation group(5.88%),and the control group(9.80%),there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of Xiyanping injection in the treatment of upper respiratory tract infection in children can effectively shorten the disappearance of symptoms in children,improve clinical efficacy,and be safe and reliable.

关 键 词：上呼吸道感染 喜炎平 安全性 

分 类 号：R562[医药卫生—呼吸系统]