左氧氟沙星联合阿奇霉素治疗宫颈炎的临床药学分析  

Clinical Pharmaceutical Analysis of Levofloxacin Combined with Azithromycin in the Treatment of Cervicitis

作　　者：王沛 WANG Pei(Department of Pharmacy,General Hospital of Jinshui District,Zhengzhou Henan 450000,China)

机构地区：[1]郑州市金水区总医院药剂科,河南郑州450000

出　　处：《药品评价》2020年第5期62-64,共3页Drug Evaluation

摘　　要：目的:研究左氧氟沙星联合阿奇霉素治疗宫颈炎的临床效果。方法:回顾分析我院2016年11月至2018年4月收治宫颈炎患者66例为研究对象,抽签法分观察组(左氧氟沙星联合阿奇霉素)与对照组(阿奇霉素)各33例,比较两组炎性因子水平、治疗效果与不良反应。结果:治疗前两组炎性因子水平无差异,P>0.05;治疗后观察组白细胞介素-6、超敏C反应蛋白与肿瘤坏死因子-α水平较对照组低,两组组内数据也存在差异;与对照组比较,观察组治疗效果高,不良反应发生率与复发率低,P<0.05(具有统计学差异)。结论:对宫颈炎患者采用左氧氟沙星联合阿奇霉素治疗能降低炎性因子水平,提高疗效避免疾病复发,值得推荐。Objective:To study the clinical effect of levofloxacin combined with azithromycin in the treatment of cervicitis.Methods:66 patients with cervicitis in our hospital from November 2016 to April 2018 were retrospectively analyzed.33 patients in the observation group(levofloxacin combined with azithromycin)and 33 patients in the control group(azithromycin)were selected by lot method.The levels of inflammatory factors,therapeutic effects and adverse reactions were compared between the two groups.Results:Before treatment,there was no difference in the levels of inflammatory factors between the two groups(P>0.05);after treatment,the levels of interleukin-6,hypersensitive C-reactive protein and tumor necrosis factoralpha in the observation group were lower than those in the control group,and the data in the two groups were also different;compared with the control group,the treatment effect of the observation group was higher,the incidence of adverse reactions and recurrence rate were lower,P<0.05(with statistical difference).Conclusion:Levofloxacin combined with azithromycin can reduce the level of inflammatory factors,improve the curative effect and avoid recurrence of cervicitis,which is worthy of recommendation.

关 键 词：左氧氟沙星 阿奇霉素 宫颈炎 临床效果 

分 类 号：R984[医药卫生—药品]