膜分离技术在金边土鳖活性成分分离中的应用  

Application of membrane separation technology in the separation of active omponents from phnom penh turtle

作　　者：冯敬文 黄桂芬 江建航 许文杰 FENG Jing-wen;HUANG Gui-fen;JIANG Jian-hang;无(Chinese Medicine Hospital of Panyu District,Guangzhou City,Guangzhou 511400,China;The Second Traditional Chinese Medicine Hospital of Guangdong Province,Guangzhou 510000,China)

机构地区：[1]广州市番禺区中医院,广州511400 [2]广东省第二中医院,广州510000

出　　处：《中国处方药》2020年第7期34-36,共3页Journal of China Prescription Drug

基　　金：广东省中医药局科研项目(20181019)。

摘　　要：目的探索振动膜分离技术在金边土鳖活性成分分离的工艺条件。方法以金边土鳖匀浆液为研究对象,对匀浆液特性进行研究,以活性成分转移率、固形物清除率及膜通量为考察指标,评价振动膜应用的可行性。结果确定最佳膜分离条件:30℃的匀浆液原液、0.35 MPa操作压力、振幅5 mm、截留相对分子量4万,活性成分转移率达到88%,除杂率达到50%。结论膜分离技术适合用于金边土鳖活性成分分离纯化的生产中。Objective Vibiation shcar enhanced proccssing(VSEP)Membrane separation technology was applied to active components in Opisthoplatia Orientalis Burm.in the process of extraction and purification.To explore the optimal specification parameters.Methods The Study object is based on physical and chemical parameters of Opisthoplatia Orientalis Burm.homogenate,to evaluate the feasibility of VSEP technology with active components transfer rate and solid removal rate.Results The optimized operation conditions were as follow:30℃crude solution with an ultrafiltration membrane with relative molecular weight cut of 40 thousand,at the amplitude of 5 mm,under 0.35 Mpa operation pressure.In this condition,the active components total transfer rate was 88%,solid removal rate was up to 50%.Conclusion Membrane separation technology Can effectively improve the quality of Opisthoplatia Orientalis Burm.and can be used in active components seraration proccss.

关 键 词：膜分离 金边土鳖 振动膜 超滤 

分 类 号：R284.2[医药卫生—中药学]