2017~2019年某院常用抗痛风药使用情况分析  

Analysis on the use of common anti-gout drugs in our hospital from 2017 to 2019

作　　者：郑俊德 卓少华[1] 洪怀章 郭林[1] 丘远聪[1] ZHEN Jun-de;ZHUO Shao-hua;HONG Huai-zhang(Department of Pharmacy,Huizhou First Hospital,Guangdong 516000,China)

机构地区：[1]惠州市第一人民医院药学部,广东惠州516000

出　　处：《中国处方药》2020年第7期61-62,共2页Journal of China Prescription Drug

摘　　要：目的通过整理及分析2017~2019年医院常用抗痛风药使用情况,为临床合理用药及降低用药成本提供参考。方法通过HIS系统、药品不良反应数据库统计常用抗痛风药品种、年销售金额、DDC、DDDs、不良反应例数等来分析使用情况。结果别嘌醇DDC由2.32元上涨至6.60元,DDDs逐年降低,ADR共18例,多为皮疹。秋水仙碱DDC 0.27元上涨至0.49,DDDs上涨一年后下降,ADR共27例,表现为皮疹多见。苯溴马隆DDC维持不变,DDDs逐年上涨,为常用抗痛风药中使用频度最大,ADR共14例,表现为腹泻、腹痛。结论某院抗痛风急性发作治疗以秋水仙碱药物为一线药物,对痛风发作预防性治疗以苯溴马隆、别嘌醇为一线药物,其中以苯溴马隆选择倾向性最大。Objective To analyze the use of common anti-gout drugs in our hospital from 2017 to 2019,so as to provide a reference for drug use plan with reasonable clinical value and high economic cost.Methods HIS system and ADR database were used to analyze the use of common Allopurinol,the annual sales amount,DDC,DDDs and the number of adverse reactions.Results Allopurinol DDC increased from 2.32 yuan to 6.6 yuan,and DDDs decreased year by year.Colchicine DDC 0.27 yuan increased to 0.49,DDDs rose one year after the decline,a total of 27 cases of ADR,presenting as rash.Benzodiazepine DDC remained unchanged,and DDDs increased year by year,making it the most frequently used anti-gout drug,with 14 cases of ADR,presenting with diarrhea and abdominal pain.Conclusion Colchicine was the first-line drug in the treatment of acute gout attack in our hospital,and benzobromalone and allopurinol were the first-line drugs in the preventive treatment of gout attack.

关 键 词：抗痛风药 苯溴马隆 别嘌醇 秋水仙碱 使用情况 

分 类 号：R971.1[医药卫生—药品]