新型冠状病毒肺炎合并高血压患者心肌CT影像学特点分析  

The myocardial CT imaging characteristics of patients with COVID⁃19 combined with hypertension

作　　者：沈国秀 顾崇怀 孙爱娇[2] 乔锐[2] 徐健 SHEN Guoxiu;GU Chonghuai;SUN Aijiao;QIAO Rui;XU Jian(Department of Cardiovascular Medicine,Pro⁃vincial Hospital Affiliated to Anhui Medical University,the First Affiliated Hospital of China University of Science and Technology,Hefei 230001,China;不详)

机构地区：[1]安徽医科大学附属省立医院,中国科学技术大学附属第一医院心血管内科,合肥230001 [2]安庆市立医院,安徽医科大学附属安庆医院心血管内科,安徽安庆246000

出　　处：《实用医学杂志》2020年第13期1716-1720,共5页The Journal of Practical Medicine

基　　金：安徽医科大学校基金项目(编号:2018xkj076)。

摘　　要：目的探究新型冠状病毒感染肺炎(COVID-19)合并高血压病患者心肌损伤实验室及影像学特点。方法回顾性分析安庆市立医院2020年1月22日至3月4日收治的COVID-19患者,将其按照是否合并高血压病分为两组。比较两组患者在院期间相关实验室指标,并通过电子计算机断层扫描(CT)获取其住院期间首次及出院前相应心肌CT值及心外膜脂肪(EAT)体积,分析COVID-19合并高血压病患者心肌影像学特点。结果比较两组患者一般资料,患者在年龄、性别、基础疾病构成等方面差异无统计学意义(P>0.05)。两组患者在包括hs-TNT在内的基线实验室化验指标上差异无统计学意义(P>0.05),但合并高血压的COVID-19患者hs-TNT峰值较未合并高血压的患者显著升高[4.00(3.00,6.00)vs. 9.50(6.95,10.45),P=0.003]。比较两组CT影像学特点发现:无论是基线还是出院前患者心肌CT值均差异无统计学意义(P>0.05)。两组基线EAT体积差异无统计学意义(P=0.176),高血压组患者出院前EAT体积较非高血压组患者明显升高[(180.09±33.13)vs.(114.63±42.30),P<0.001],同时对比两组出-入院EAT体积差值发现高血压组患者EAT体积显著增加[(59.89±24.62)vs.(13.43±21.18),P=0.004]。结论 COVID-19合并高血压的患者hs-TNT峰值及经院内CT测量的EAT体积较未合并高血压病患者均显著升高,提示可能该病对于合并高血压病患者存在潜在心肌损伤的可能。Objective This study was aimed to explore the laboratory and imaging features of myocardial injury in COVID⁃19 patients complicated with hypertension.Methods The patients with COVID⁃19 admitted in Anqing Municipal Hospital from January 22 to March 4,2020 were retrospectively analyzed and divided into two groups,according to whether complicated with hypertension or not.The relevant laboratory indexes were compared between the two groups during hospitalization,and the related indexes of myocardial injury were compared.The corresponding myocardial CT value and EAT volume during hospitalization and before discharge were obtained by CT.The characteristics of myocardial imaging in patients with COVID⁃19 complicated with hypertension were analyzed.Results Compared with the general data of the two groups,there were no significant differences in age,gender and the composition of basic diseases between the two groups(P>0.05).There was no difference in baseline laboratory tests including hs⁃TNT between the two groups,but the peak value of hs⁃TNT in COVID⁃19 patients with hypertension was significantly higher than those without hypertension[4.00(3.00)vs.9.50(6.95),P=0.003].Comparing the characteristics of CT,we found that there was no significant difference in myocardial CT value either baseline or before discharge(P>0.05).There was also no significant difference in baseline EAT volume in two groups(P=0.176).The EAT volume in the hypertension group was significantly higher than that in the non⁃hypertension group before discharge(180.09±33.13 vs.114.63±42.30,P<0.001).While compared with the difference between the discharge⁃admission EAT volume changes,we found that EAT volume in the hypertension group significantly increased(59.89±24.62 vs.13.43±21.18,P=0.004).Conclusion The peak value of hs⁃TNT and the volume of EAT measured by CT in COVID⁃19 patients with hypertension were significantly higher than those without hypertension,wihch suggested that this disease may have potential myocardial injury in pa

关 键 词：严重急性呼吸综合征冠状病毒2 新型冠状病毒肺炎 高血压病 心外膜脂肪组织 

分 类 号：R512.99[医药卫生—内科学]