新型冠状病毒肺炎对心血管系统影响  

Effects of COVID-19 on cardiovascular system

作　　者：杨毅[1] 鲁旭然 刘楠[1] 侯晓彤[1] 孙立忠[2] 吴龙[3] 潘友民[4] 王守凤[1] 赵欣艳[1] Yang Yi;Lu Xuran;Liu Nan;Hou Xiaotong;Sun Lizhong;Wu Long;Pan Youmin;Wang Shoufeng;Zhao Xinyan(Center for Cardiac Intensive Care,Beijing Anzhen Hospital,Capital Medical University,Beijing Institute of Heart Lung and Blood Vessel Diseases,Beijing 100029,China;Department of Cardiac Surgery,Beijing Anzhen Hospital,Capital Medical University,Aortic Disease Center of Beijing Institute of Heart Lung and Blood Vessel Diseases,Beijing 100029,China;Department of Cardiovascular Surgery,Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430022,China;Department of Cardiovascular Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430030,China)

机构地区：[1]首都医科大学附属北京安贞医院心外科危重症中心北京市心肺血管疾病研究所,北京100029 [2]首都医科大学附属北京安贞医院心脏外科北京市心肺血管疾病研究所北京市大血管疾病诊疗研究中心,北京100029 [3]华中科技大学同济医学院附属协和医院心脏大血管外科,武汉430022 [4]华中科技大学同济医学院附属同济医院外科大血管外科,武汉430030

出　　处：《首都医科大学学报》2020年第4期657-663,共7页Journal of Capital Medical University

基　　金：国家科技支撑计划项目(2015BAI12B03);北京市科技重大专项课题(Z171100001017083)。

摘　　要：新型冠状病毒肺炎(COVID-19)除了典型呼吸系统症状,也有一定比例COVID-19患者出现了心血管系统受损的临床表现且此类患者进展为重症或死亡的概率较高。目前对于COVID-19的病理机制尚未完全了解,心血管系统的变化也有待进一步分析研究。本文综合目前已有文献,分析与初步探索心血管系统可能的损伤机制,包括病毒直接损伤心肌细胞及传导系统,合并症或伴随情况如低氧血症、炎性反应、应激等对心血管系统的损害以及药物的影响等。In addition to typical respiratory system symptoms,some patients with COVID-19 have a clinical presentation of cardiovascular impairment.Such patients are more likely to progress to severe illness or death.However,the pathological mechanism of COVID-19 is not yet fully understood,and the changes of cardiovascular system need further analysis and research.Based on the existing literature,this paper preliminarily reviewed the possible damage mechanism of cardiovascular system,including the direct damage of myocardial cells and conduction system by virus,the damage of cardiovascular system by complications or accompanying conditions such as hypoxemia,inflammatory response,stress,and the influence of drugs.

关 键 词：新型冠状病毒肺炎 心血管系统 多脏器衰竭 

分 类 号：R563.1[医药卫生—呼吸系统]