超声引导下射频消融术治疗乳腺良性结节的临床效果  

Ultrasound-guided Radiofrequency Ablation for the Treatment of Benign Breast Nodules

作　　者：崔怀信[1] 王鹏[2] 厉志洪 陈烨[2] 王东玮[2] 娄可新 CUI Huai-xin;WANG Peng;LI Zhi-hong;CHEN Ye;WANG Dong-wei;LOU Ke-xin(General Surgery Department,Xuzhou Central Hospital,Xuzhou 221009,Jiangsu,China;Ultrasound Department,Xuzhou Central Hospital,Xuzhou 221009,Jiangsu,China)

机构地区：[1]徐州市中心医院普外科,江苏徐州221009 [2]徐州市中心医院超声科,江苏徐州221009

出　　处：《医学信息》2020年第13期103-105,共3页Journal of Medical Information

基　　金：江苏省徐州市科技资助项目(编号:KC16SY161)。

摘　　要：目的探讨超声引导下射频消融术(RFA)治疗乳腺良性结节的临床效果。方法回顾性分析2016年11月~2018年6月于我院接受超声引导下射频消融治疗的58例(共78个结节)乳腺良性结节患者的临床资料,记录每个消融灶手术前、手术后3、6、12个月时体积及消融灶弹性Ratio比值变化情况,将结节分为直径<1 cm与直径在1~3 cm,分析结节大小与消融体积缩小率的相关性。结果①消融后超声造影未见明显增强,1个月后77个结节完全凝固坏死,仅1个结节超声造影显示不完全消融,准备二次消融或手术治疗;②手术后,患者消融灶体积较手术前逐渐缩小,患者消融灶体积减小率逐渐增高,差异有统计学意义(P<0.05);各时间点患者弹性Ratio比值均较治疗前呈上升趋势,差异有统计学意义(P<0.05);③手术前与手术后每个月消融灶弹性Ratio比值与手术前后消融灶体积呈负相关(r=-4.913,P<0.05);手术前与手术后每个月消融灶弹性Ratio比值与术后消融灶体积缩小率呈正相关(r=0.014,P<0.05);④术后各时间点1~3 cm的结节消融灶体积缩小率均高于<1 cm的结节,差异具有统计学意义(P<0.05)。结论超声引导下射频消融术治疗乳腺良性结节效果确切,且直径1~3 cm的结节术后消融灶吸收较快,结节大小可能会影响患者术后消融灶的吸收效果。Objective To explore the clinical effect of ultrasound-guided radiofrequency ablation(RFA)in the treatment of benign breast nodules.Methods The clinical data of 58 patients(78 nodules)with benign breast nodules who received ultrasound-guided radiofrequency ablation in our hospital from November 2016 to June 2018 were retrospectively analyzed.At 3,6,and 12 months after the operation,the volume and the ratio of ablation focus elastic Ratio changes.The nodules were divided into diameters less than 1 cm and diameters from 1 to 3 cm.The correlation between nodule size and ablation volume reduction rate was analyzed.Results①Ultrasonography did not show obvious enhancement after ablation,77 nodules were completely coagulated and necrotic after 1 month,only 1 nodule showed incomplete ablation,preparation for secondary ablation or surgical treatment;②After the operation,the volume of the ablation focus of the patient gradually decreased compared with that before the operation,and the rate of volume reduction of the ablation focus of the patient gradually increased,the difference was statistically significant(P<0.05);The ratio of elastic Ratio of patients at each time point showed an upward trend compared with that before treatment,and the difference was statistically significant(P<0.05);③The ratio of ablation focus elastic Ratio before and after surgery was negatively correlated with the volume of ablation focus before and after surgery(r=-4.913,P<0.05);the ratio of ablation focus elastic Ratio before and after surgery per month was postoperatively ablated the volume reduction rate of the lesion was positively correlated(r=0.014,P<0.05);④The volume reduction rate of 1~3 cm nodule ablation focus at each time point after operation was higher than that of nodule<1 cm,the difference was statistically significant(P<0.05).Conclusion Ultrasound-guided radiofrequency ablation is effective in the treatment of benign breast nodules,and the nodules with a diameter of 1 to 3 cm can be absorbed quickly after the ablation.The s

关 键 词：超声引导 射频消融术 乳腺良性结节 

分 类 号：R445.1[医药卫生—影像医学与核医学] R655.8[医药卫生—诊断学]