辽沈地区血尿酸、Cys C、血脂及尿PH与肾结石形成的相关性研究  

The relationship between uric acid,Cys C,blood lipid,urinary pH and the formation of kidney stones in Liaoshen area

作　　者：张芷境 郑伟 ZHANG ZHIjing;ZHENG Wei(Department of Clinical Laboratory,General Hospital of the Northern War Zone,Shenyang,Liaoning 110016,China)

机构地区：[1]北部战区总医院检验科,辽宁沈阳110016

出　　处：《国际检验医学杂志》2020年第S01期50-53,共4页International Journal of Laboratory Medicine

摘　　要：目的探讨肾结石与血尿酸、胱抑素C(Cys C)、血脂及尿酸碱度(PH)之间的关系。方法回顾性分析2016年3月2日至2017年4月11日在该院就诊的150例肾结石患者(结石组)及同期体检健康者100例(对照组)的外周血、尿标本。分析肾结石与血尿酸、Cys C、血脂及尿PH水平的相关性。结果所有结石成分主要以草酸钙结石为主,占94.7%。结石组的血尿酸、Cys C、血脂高于对照组,差异有统计学意义(P<0.05),而尿PH差异无统计学意义(P>0.05)。草酸钙结石组中血尿酸水平最高,差异有统计学意义(P<0.05)。结论辽沈地区高血尿酸、高血脂及高Cys C影响肾结石的形成,早期控制高尿酸、高血脂以及高Cys C是防治肾结石形成的关键。Objective To investigate the relationship between uric acid,Cys C,blood lipid,urinary pH and the formation of kidney stones.Methods The peripheral blood and urine samples of 150 patients with kidney stones(stone group)and 100 healthy patients(control group)were retrospectively analyzed from March 2,2016 to April 11,2017.The correlation between kidney stones and blood uric acid,Cys C,blood lipids and urine pH values was analyzed.Results All the stone components were mainly calcium oxalate stones which accounted for 94.7%.The blood uric acid,Cys C and blood lipids in the stone group were higher than those in the control group,and the difference was statistically significant(P<0.05),but there was no significant difference in urine PH value(P>0.05).The level of serum uric acid was the highest in the calcium oxalate stone group,and the difference was statistically significant(P<0.05).Conclusion High blood uric acid,hyperlipidemia and high Cys C in Liaoshen area may affect the formation of kidney stones.Early control of high uric acid,hyperlipidemia and high Cys C is probably the key to prevention and treatment of kidney stones.

关 键 词：肾结石 血尿酸 胱抑素C 血脂 尿酸碱度 

分 类 号：R69[医药卫生—泌尿科学]