百部中主要生物碱的药理作用研究进展  

A review on the pharmacological activities of two main alkaloids from Stemonae Radix

作　　者：祝清炜 张勉[1] Zhu Qingwei;Zhang Mian(Research Department of Pharmacognosy,China Pharmaceutical University,Nanjing,Jiangsu 211198,China)

机构地区：[1]中国药科大学生药学研究室,江苏南京211198

出　　处：《医药前沿》2020年第12期12-13,共2页Journal of Frontiers of Medicine

摘　　要：百部为我国传统中药,具有润肺止咳、杀虫灭虱的功效,主治新旧咳嗽、百日咳等。百部生物碱是一类结构独特的吡咯类生物碱,也是百部的主要化学成分和活性成分,其中新对叶百部碱和对叶百部碱是两种比较常见的百部生物碱。近年来,关于新对叶百部碱和对叶百部碱的药理作用研究不断深入,涉及到镇咳、抗肺纤维化、抗炎、抗耐药性等多个方面。对这两种生物碱的药理作用研究综述如下,有助于今后更好的开发和利用。Stemonae Radix(Baibu)is one of traditional Chinese medicines with the functions of moistening the lung and relieving cough,killing insects and lice.It is mainly used to treat new and long cough,pertussis,etc.Stamona alkaloids are a kind of pyrrole alkaloids with unique structures,which are also the main chemical and active constitutes of Baibu.Among them,neotuberostemonine and tuberostemonine are two common Stemona alkaloids.In recent years,their pharmacological activities have been deeply studied,involving antitussive,anti-pulmonary fibrosis,anti-inflammatory,anti-drug resistance and other aspects.A review on the pharmacological effects of these two alkaloids will be helpful for better development and utilization of them in the future.

关 键 词：对叶百部 新对叶百部碱 对叶百部碱 药理作用 

分 类 号：R285[医药卫生—中药学]