重建算法影响计算机辅助检测评价低剂量CT肺气肿定量和支气管成像  

Reconstruction Algorithm Affects Computer-Aided Detection in Evaluation of Low-Dose CT Emphysema Quantitative and Bronchial Imaging

作　　者：贾永军 于楠[1,2] 贺太平 段海峰[1,2] 杨创勃 于勇[1,2] JIA Yongjun;YU Nan;HE Taiping;DUAN Haifeng;YANG Chuangbo;YU Yong(Department of Radiology,Affiliated Hospital of Shaanxi Chinese Medicine University,Xianyang 712000,China;Medical Technology College of Shaanxi Chinese Medicine University,Xianyang 712000,China)

机构地区：[1]陕西中医药大学附属医院医学影像科,陕西咸阳712000 [2]陕西中医药大学,陕西咸阳712000

出　　处：《中国医学影像学杂志》2020年第7期504-507,512,共5页Chinese Journal of Medical Imaging

基　　金：国家自然科学基金(81701691);陕西省自然科学基金面上项目(2019JM-361);陕西中医药大学创新团队基金(2019-YS04)。

摘　　要：目的比较基于模型的迭代重建(MBIR)、自适应迭代重建(ASIR)和滤波反投影(FBP)重建对计算机辅助检测(CAD)低剂量CT(LDCT)条件下肺气肿定量和气道成像的影响。资料与方法收集接受胸部LDCT受检者36例,分别采用FBP、ASIR和MBIR重建。应用CAD进行肺气肿定量和提取分析右肺上叶支气管长度。由2名影像诊断医师以ASIR重建为标准,对FBP、MBIR自动提取的支气管树结构在图像伪影、气管壁连续性、气管软骨环清晰度进行盲法5分半定量评分。结果FBP、MBIR和ASIR重建图像经CAD检测的全肺体积差异无统计学意义(P>0.05)。FBP和ASIR重建图像经CAD检测得到的低衰减区百分比多于MBIR,对于全肺低衰减区百分比,与FBP重建相比,ASIR重建减少约0.36%,MBIR重建减少约10.54%,差异有统计学意义(P<0.05)。MBIR算法图像自动提取的右肺中叶支气管长度为(18.82±2.90)cm,明显长于ASIR的(13.99±3.17)cm和FBP算法的(13.23±3.12)cm,差异有统计学意义(P<0.05)。CAD自动提取FBP重建图像的支气管树成像主观评分低于ASIR,MBIR主观评分高于ASIR(P<0.05)。结论重建算法影响LDCT评价肺气肿定量和支气管分析,在采用CAD随访和预测COPD严重程度时需确定重建算法;MBIR在支气管分析中有重要价值。Purpose To compare model-based iterative reconstruction(MBIR),adaptive statistical iterative reconstruction(ASIR)and filtered back projection(FBP)reconstruction for quantitative and airway analysis of computer-aided detection(CAD)for chest low-dose CT(LDCT).Materials and Methods Thirty-six patients who underwent chest LDCT were enrolled in this study,then reconstructed with FBP,ASIR and MBIR respectively.CAD was used to quantify and extract emphysema,the length of the right upper lobe bronchus was analyzed.Based on ASIR reconstruction,the two bronchial tree structures extracted by FBP and MBIR were visually scored on the image artifacts,tracheal wall continuity and tracheal cartilage ring clarity by two imaging diagnosticians using 5 and a half quantification.Results FBP,MBIR and ASIR reconstructed images showed no statistically significant difference in the total lung volume detected by CAD(P>0.05).Compared with FBP reconstruction,the low attenuation areas volume percentage(LAA%)obtained by CAD detection of FBP and ASIR reconstructed images was higher than that of MBIR.Compared with FBP reconstruction,ASIR reconstruction was reduced by about 0.36%,MBIR reconstruction was reduced by about 10.54%,with statistically significant difference(P<0.05).The length of the middle lung lobe bronchus automatically extracted by MBIR algorithm image was(18.82±2.90)cm,which was significantly longer than that of(13.99±3.17)cm in ASIR and(13.23±3.12)cm in FBP algorithm,with significant difference(P<0.05).The subjective score of bronchial tree imaging automatically extracted by CAD FBP reconstructed was lower than that of ASIR,and MBIR subjective score was higher than ASIR(P<0.05).Conclusion The reconstruction algorithm affects the LDCT evaluation of emphysema quantitative and bronchial analysis.When using CAD to follow up and predict the severity of COPD,the reconstruction algorithm needs to be determined;MBIR has important value in bronchial analysis.

关 键 词：肺气肿 肺疾病 慢性阻塞性 体层摄影术 X线计算机 迭代重建技术 算法 计算机辅助检测 图像处理 计算机辅助 辐射剂量 

分 类 号：R445.3[医药卫生—影像医学与核医学] R563.3[医药卫生—诊断学]