结核性胸膜炎胸腔积液患者应用利福霉素钠的临床效果  

Clinical Effect of Rifamycin Sodium in Patients with Tuberculous Pleurisy and Pleural Effusion

作　　者：常娟 CHANG Juan(Department of Tuberculosis,Liangshan County People's Hospital,Liangshan,Shandong Province,272600 China)

机构地区：[1]梁山县人民医院结核科,山东梁山272600

出　　处：《系统医学》2020年第10期75-77,共3页Systems Medicine

摘　　要：目的分析结核性胸膜炎胸腔积液患者应用利福霉素钠的临床效果。方法择取2016年10月—2019年10月时间段内于该院接受治疗的86例结核性胸膜炎胸腔积液患者展开研究分析,按照随机数字表法划分成两组,即观察组(43例)、对照组(43例),对照组治疗方案为2HRZE/10HR化疗+胸膜腔穿刺抽液+胸腔注入异烟肼、地塞米松,观察组治疗方案为2HRZE/10HR化疗+胸膜腔穿刺抽液+胸腔注入利福霉素钠、地塞米松;对比分析两组临床治疗有效率、抽液次数、积液消失时间以及不良反应发生率。结果观察组临床治疗有效率93.02%高于对照组74.42%,组间差异有统计学意义(χ^2=5.460,P<0.05);观察组抽液次数(2.15±0.45)次少于对照组(5.10±1.32)次,且积液消失时间(6.90±1.35)d短于对照组(13.50±4.45)d,相应数据对比差异有统计学意义(t=13.871、9.307,P<0.05)。结论结核性胸膜炎胸腔积液患者应用利福霉素钠的临床效果较为可靠,且抽液次数较少,积液消失快,不良反应风险较低,对患者预后有良好的促进作用。Objective To analyze the clinical effect of rifamycin sodium in patients with tuberculous pleurisy and pleural effusion. Methods A total of 86 patients with tuberculous pleurisy and pleural effusion who were treated in the hospital from October 2016 to October 2019 were selected and analyzed. They were divided into two groups according to the random number table method, namely the observation group(43 cases), the control group(43 cases), the treatment plan of the control group was 2 HRZE/10 HR chemotherapy + pleural cavity puncture pumping liquid +infusion of isoniazid and dexamethasone, and the observation group was treated with 2 HRZE/10 HR chemotherapy +pleural cavity puncture pumping solution + Intrathoracic injection of rifamycin sodium and dexamethasone;comparison and analysis of clinical treatment effectiveness, number of aspirations, disappearance of effusion, and incidence of adverse reactions between the two groups. Results The effective rate of clinical treatment in observation group was93.02% higher than that in control group 74.42%, and the difference between groups was statistically significant(χ^2=5.460, P<0.05). The number of pumps(2.15±0.45)times in observation group was less than(5.10±1.32)times in control group. The disappearance time of effusion(6.90±1.35)d was shorter than that of the control group(13.50±4.45)d, and the corresponding data comparison showed the statistically significantly difference(t=13.871,9.307,P<0.05). Conclusion The clinical effect of rifamycin sodium in tuberculous pleurisy patients with pleural effusion is more reliable, and the number of fluid withdrawals is less, the effusion disappears quickly, the risk of adverse reactions is lower, and it has a good promotion effect on patients.

关 键 词：结核性胸膜炎 胸腔积液 利福霉素钠 抽液情况 

分 类 号：R521.7[医药卫生—内科学]