伊曲康唑在甲真菌病治疗中的应用  

Application of itraconazole in the treatment of onychomycosis

作　　者：姜伟伟[1] 扈东营 方文捷[1] 张蕾[1] 邓宇晨 李航 王会伟 陈显振 廖万清[1] 潘炜华[1] 徐顺明[2] JIANG Wei-wei;HU Dong-ying;FANG Wen-jie;ZHANG Lei;DENG Yu-chen;LI Hang;WANG Hui-wei;CHEN Xian-zhen;LIAO Wan-qing;PAN Wei-hua;XU Shun-ming(Department of Dermatology,Shanghai Changzheng Hospital,Shanghai 200003,China;Department of Dermatology,Shanghai Pudong New Area People's Hospital,Shanghai 201200,China)

机构地区：[1]上海长征医院皮肤科,上海200003 [2]上海浦东新区人民医院皮肤科,上海201200

出　　处：《世界临床药物》2020年第5期329-333,共5页World Clinical Drug

基　　金：“海上丝绸之路”重要病原体的威胁感知和监测预警(2018ZX10101003);上海市真菌病与自身免疫性疾病临床医学中心(2017ZZ01024-001);上海市扬帆计划(19YF1448000);中国工程院战略咨询课题(2017-XY-35,2019-XY-33,19-HN-XZ-06,2020-XY-61-01)。

摘　　要：甲真菌病(onychomycosis)是一种临床高发的浅部真菌感染,易反复、难根治。伊曲康唑(itraconazole)对引起甲真菌病的皮肤癣菌、酵母菌和非皮肤癣菌性霉菌等均具有良好的抗菌活性,是目前临床上被广泛用于甲真菌病治疗的药物。本文旨在对伊曲康唑胶囊剂在甲真菌病治疗中的应用研究进行综述。Onychomycosis is a kind of superficial fungal infection with high clinical incidence,which is easy to be repeated and difficult to cure.Itraconazole has good antibacterial activity against dermatophytes,Yeasts and nondermatophytic molds causing onychomycosis.Itraconazole is widely used in clinical treatment of onychomycosis.The purpose of this article was to review the application of itraconazole capsules in the treatment of onychomycosis.

关 键 词：伊曲康唑 甲真菌病 联合治疗 

分 类 号：R978.5[医药卫生—药品] R756.4[医药卫生—药学]