OSMS在腹部肿瘤放疗摆位中的应用  

Application of OSMS in positioning for abdominal tumor radiotherapy

作　　者：叶峰[1] 翟振宇[1] 牟忠德 YE Feng;ZHAI Zhenyu;MU Zhongde(Department of Radiotherapy,Jiangsu Cancer Hospital,Nanjing 210009,China)

机构地区：[1]江苏省肿瘤医院放疗科,江苏南京210009

出　　处：《中国医学物理学杂志》2020年第7期828-833,共6页Chinese Journal of Medical Physics

基　　金：江苏省肿瘤防治研究所博士后经费(SZL201715)。

摘　　要：目的:通过与锥形束计算机断层扫描(CBCT)参照对比,探讨光学表面监测系统(OSMS)在腹部肿瘤放疗中摆位的作用,探讨OSMS的摆位精度及其应用价值。方法:选取4名腹部肿瘤患者,应用体表“+”标记与激光灯进行治疗前摆位,行CBCT同时进行OSMS运行前的验证,分别记录OSMS和CBCT提供的配准信息,记录X(左右)、Y(头脚)与Z(前后)方向的平移误差。应用Pearson方法分析摆位误差的相关性、系统误差与随机误差,并用Bland-Altman方法评估OSMS的置信空间。计算常规方法摆位以及经过OSMS摆位后95%的剂量偏移靶区体积的k值。结果:研究发现OSMS与CBCT的摆位精度具有很好的相关性,X、Y与Z方向的相关系数分别为0.628、0.858、0.682。OSMS摆位在X、Y与Z方向的系统误差±随机误差分别为(0.01±0.33)、(-0.14±0.64)、(0.13±0.41)mm,k值为(0.8019±0.7044)%。结论:OSMS在实际应用中体现出与CBCT配准数据的一致性,可以摆脱CBCT的引导独立使用,精度较高。Objective To investigate the role of optical surface monitoring system(OSMS)in the positioning for abdominal tumor radiotherapy by comparing with CBCT-based positioning,and to explore the positioning accuracy of OSMS and its application value.Methods Four patients with abdominal tumor were enrolled.The"+"mark on the body surface and laser lamp were used to realize pre-treatment positioning.During CBCT examination,OSMS was verified before operation.The registration information provided by OSMS and CBCT was recorded separately,and translational errors in X(left-right),Y(head-foot)and Z(front-back)directions were recorded.Pearson method was used for analyzing positioning errors,systematic errors and random errors,and Bland-Altman method for evaluating the confidence interval of OSMS.The k value of 95%dose-shifted target volume after positioning by the conventional method or OSMS was calculated.Results There was a good correlation between the positioning accuracy of CBCT and that of OSMS,and the correlation coefficients were 0.628,0.858 and 0.682 in X,Y and Z directions,respectively.The systemic error±random error of OSMS positioning were(0.01±0.33),(-0.14±0.64)and(0.13±0.41)mm in X,Y and Z directions,respectively,and the k value was(0.8019±0.7044)%.Conclusion OSMS in the actual application has a high consistency with CBCT registration data.OSMS which has a high accuracy in positioning can be used independently without the guidance of CBCT.

关 键 词：腹部肿瘤 光学表面监测系统 摆位误差 

分 类 号：R815[医药卫生—放射医学]