复方增免散对雏鸡传染性法氏囊病疫苗免疫效果的影响  

Effects of Zengmiansan on the Immunological Response to Infectious Bursal Disease Vaccine in Chickens

作　　者：孟志敏 黄占欣 赵达 魏淑玲 MENG Zhi-min;HUANG Zhan-xin;ZHAO Da;WEI Shu-ling(Life Science and Food Engineering School of Hebei University of Engineering,Handan 05216,China;Shijiazhuang Jiangshan Animal Pharmaceutical Co.,Ltd,Shijiazhuang 052160,China;Agricultural Broadcasting and Television School of Luquan Shijiazhuang,Shijiazhuang 050200,China)

机构地区：[1]河北工程大学生命科学与食品工程学院,河北邯郸056000 [2]河北省石家庄市藁城区畜牧工作总站,河北石家庄052160 [3]河北省农业广播电视学校石家庄市鹿泉区分校,河北石家庄050200

出　　处：《中国兽医杂志》2020年第2期36-38,41,共4页Chinese Journal of Veterinary Medicine

基　　金：河北省科技计划项目(16222701D)。

摘　　要：为了探讨增免散对鸡传染性法氏囊病疫苗免疫效果的影响,本试验将增免散以低(0.5%)、中(1%)、高(1.5%)剂量拌料饲喂6日龄雏鸡,连喂7 d,13日龄用法氏囊病疫苗免疫;分别于21、28、35、42日龄测定雏鸡的脾脏和法氏囊指数;于20、27、34日龄ELISA测定外周血中传染性法氏囊病病毒(IBDV)抗体,同时测定外周血中IL-2、TNF-α的含量。结果表明:增免散能促进脾脏和法氏囊成长发育;可显著提高外周血中IBDV抗体滴度、IL-2和TNF-α的含量。说明增免散有明显的免疫促进作用。In order to explore the effect of Zengmiansan on infectious bursal disease(IBD) vaccine in chickens. 6-day-old chickens were feed with Zengmiansan at low(0.5%), middle(1%) and high(1.5%) dosages for 7 days. On 13th days, the chickens were vaccinated with IBD vaccine. On 21th,28th,35th and 42th days after vaccination spleen index and fabricius bursa index were determined. On 20th,27th and 34th days after vaccination the antibody levels to IBDV, contents of IL-2 and TNF-α were determined. The results showed that Zengmiansan promoted the development of the spleen and bursa. Zengmiansan also significantly increased the IBDV antibody levels, and IL-2 and TNF-α contents in the blood. The results suggest that Zengmiansan has an obvious immune boosting effect.

关 键 词：增免散 免疫器官指数 IBDV抗体 IL-2 TNF-α 雏鸡 

分 类 号：S853.75[农业科学—临床兽医学]