生物材料在腹壁疝治疗中的现状和前景  

Current status and prospect of biological materials in the treatment of ventral hernia

作　　者：唐健雄 黄磊 李绍杰 Tang Jianxiong;Huang Lei;Li Shaojie(Department of General Surgery,Hernia and Abdominal Wall Surgery,Huadong Hospital,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华东医院普外科疝和腹壁外科治疗与培训中心,上海200040

出　　处：《中华消化外科杂志》2020年第7期720-724,共5页Chinese Journal of Digestive Surgery

基　　金：上海市科委产学研医项目(19DZ1930802);市级医院新兴前沿技术联合攻关项目(SHDC12016123)。

摘　　要：现代疝修补手术的目的是修复腹壁缺损和恢复腹壁功能,消除可能发生的并发症,提高患者的生命质量。完美的疝补片,需同时兼顾理想的抗张强度和最佳的生物相容性。目前已有多种疝相关补片可使疝患者获益,但仍无一种补片能同时满足不同患者、不同疝类型、不同手术技术的需求。近10年来,生物补片在腹壁疝领域进行了大量临床实践,取得一定疗效,但也存在问题值得临床医师总结和反思。笔者认为:未来以组织诱导性生物材料为代表的一系列功能性生物材料,可能是最接近理想化的疝补片。The purpose of modern hernia surgery is to repair the defects of abdominal wall and restore abdominal wall function,eliminate all complications,and improve the quality of life in patients ultimately.A kind of"PERFECT"patch should not only has ideal tensile strength,but also has the optimal biocompatibility.Although many kinds of patches are beneficial to hernia patients,there is still no universal patch that can be used at any time,in any patient,in any kind of hernia and by any surgical technique.In the past 10 years,biological patch has been used in the field of abdominal wall hernia and achieved certain curative effects,but there are also some problems which are worthy of summary and reflection.In the future,a series of functional biomaterials represented by"tissue-induced biomaterials"may be the closest patch to"IDEALIZATION"in our time.

关 键 词：疝 腹股沟疝 腹壁切口疝 造口旁疝 生物补片 材料 

分 类 号：R656.2[医药卫生—外科学] R318.08[医药卫生—临床医学]