体素内不相干运动在椎体骨质疏松评价中的应用价值  

Application of intravoxel incoherent motion in the evaluation of vertebral osteoporosis

作　　者：黄满华[1] 蔡新宇[1] 胡新杰[1] 康金平[1] 冉小军[1] 熊浩[1] HUANG Manhua;CAI Xinyu;HU Xinjie;KANG Jinping;RAN Xiaojun;XIONG Hao(Department of Radiology,the First Prople's Hospital of Jingchou Jingzhou,Hubei Province 434000,China)

机构地区：[1]荆州市第一人民医院放射科,湖北荆州434000

出　　处：《实用放射学杂志》2020年第7期1103-1106,共4页Journal of Practical Radiology

摘　　要：目的 探讨IVIM在椎体骨质疏松评价的应用价值.方法 纳入42例骨质疏松患者及38例健康志愿者,进行双能X线吸收法(DXA)、常规DWI和IVIM成像,测量椎体的骨矿物密度(BMD)、ADC、慢速扩散系数(D)、快速扩散系数(D^*)及灌注分数(f),比较健康志愿者及骨质疏松患者的ADC和IVIM参数,采用Spearman相关性分析ADC值、IVIM参数与骨密度值(T)的相关性.结果 健康志愿者的ADC值、D值、D^* 值和f值分别为(0.50±0.08)×10^-3 mm^2/s、(0.45±0.09)×10^-3 mm^2/s、(14.42±3.01)×10^-3 mm^2/s和(0.12±0.04)%,而骨质疏松患者的ADC值、D值、D^*值和f值分别为(0.53±0.08)×10^-3 mm^2/s、(0.39±0.06)×10^-3 mm^2/s、(11.29±3.37)×10^-3 mm^2/s和(0.13±0.03)%.骨质疏松患者的D、D^*值显著低于健康志愿者(P<0.05),并和BMD值之间呈中度正相关,相关系数分别为0.590和0.702,而ADC值和f值无统计学差异,且和BMD无相关性.结论 骨质疏松患者的D、D^*值下降,BMD存在一定相关性,IVIM成像可作为DXA的有效补充,是一种无创评价骨质疏松的方法.0bjective To investigate the diagnostic value of IVIM in the evaluation of vertebral osteporosis.Methods A totul of 42 patients with osteoporosis and 38 healthy volunteers were enrolled in this study.All subjects were underwent dual-energy X-ray absorptiomery(DXA),conventional DWI and IVIM imaging examination.Bone mineral density(BMD),ADC,D,Dand f of the vertebral body were measured,repectively.ADC value and IVIM prrameters were compured between healthy volunters and asteoporasis patients.Sprarman correlation was used to analyxe the correlation between ADC value,IVIM parameters and bone mineral density values(T).Results The ADC value,D value,D'value and f value were (0.50±0.08)×10^-3 mm^2/s,(0.45±0.09)×10^-3 mm^2/s.(14.42±3.01)×10^-3 mm^2/s and(0.12±0.04)%for healthy wounter,sand (0.53±0.08)×10^-3 mm^2/s,(0.39±0.06)×10^-3 mm^2/s(11.29±3.87)×10^-3 mm^2/s and (0.13±0.03)%for nteporosi paiense,repertively.The D and D'values of osteoporosis patients were significantly lower than that of bealthy volunteers(P<0.05),and there was a moderate positive correlation with BMD values.The crrelation coffcients were 0.590 and 0.702,repetirvely.The ADC and f values showod no strtistical dfference between osteoporosis patients and bealthy wolunteers,also demonstrated no corelation with BMD.Conclusion The D and D'valuxs are decreased in osteoporoeis,and show moderate crelntion with BMD.The IVIM imaging can be uwed 8 an eeetive supplemwmnt 10 DXA.providing a non imwe metbod for eraluating osteoporosis.

关 键 词：骨质疏松 骨矿物密度 体素内不相干运动 

分 类 号：R681[医药卫生—骨科学] R445.2[医药卫生—外科学]