钯催化氧杂降冰片烯与三氟硼酸钾盐的不对称开环反应  

Palladium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadienes with Potassium Trifluoroborate Salts

作　　者：陶萍芳 黄俊 刘玉钊 韦光明 王艺菲 韦贤生 黄国保 李秀英 Tao Pingfang;Huang Jun;Liu Yuzhao;Wei Guangming;Wang Yifei;Wei Xiansheng;Huang Guobao;Li Xiuying(Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology,College of Chemistry and Food Science,Yulin Normal University,Yulin,Guangxi 537000;College of Chemistry and Materials,Nanning Normal University,Nanning 530001)

机构地区：[1]玉林师范学院化学与食品科学学院/广西农产资源化学与生物技术重点实验室,广西玉林537000 [2]南宁师范大学化学与材料学院,南宁530001

出　　处：《有机化学》2020年第6期1630-1637,共8页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21971204,216222203,21702161);陕西省创新能力支撑计划(No.2020TD-022);陕西省教育厅科学基金(No.19JS064)资助项目.

摘　　要：开发了一种新型高效的钯催化的三氟硼酸钾盐与氧杂降冰片烯的不对称开环反应的方法.在温和的条件下,可得到相应的顺-2-芳基-1,2-二氢萘-1-醇产物,其产率良好,目标产物对映体选择性较高.A new,versatile and highly efficient palladium-catalyzed asymmetric ring-opening reaction of oxabenzonorbornadienes with a wide range of potassium trifluoroborate salts was developed.The corresponding cis-2-aryl-1,2-dihydronaphthalen-1-ol products were obtained in good yields with moderate to good enantioselectivities under mild conditions.

关 键 词：氧杂降冰片烯 三氟钾硼酸盐 不对称开环反应 

分 类 号：O621.251[理学—有机化学]