新型通用型粘接剂对牙本质粘接强度的体外研究  

Evaluation of bond strength of new universal adhesives to dentin a vitro study

作　　者：李苑 苏毅[1,2] 江飞[1,3] 刘丽[1,2] 瞿灵丽 LI Yuan;SU Yi;JIANG Fei;LIU Li;QU Lingli(Jiangsu Key Laboratory of Oral Diseases,Nanjing Medical University,Nanjing 210029,China;Department of the Third Clinic,the Affiliated Stomatological Hospital of Nanjing Medical University,Nanjing 210029,China;Department of General Dentistry,the Affiliated Stomatological Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学口腔疾病研究江苏省重点实验室,江苏南京210029 [2]南京医科大学附属口腔医院第三门诊部,江苏南京210029 [3]南京医科大学附属口腔医院综合诊疗科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2020年第5期754-758,762,共6页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省科技厅基础研究计划(自然科学基金)—青年基金项目(BK20180671)。

摘　　要：目的:评价3种通用型粘接剂和1种第7代粘接剂粘接牙本质在酸蚀-冲洗和自酸蚀处理模式下即刻和老化后微拉伸强度的差别。方法:128颗无龋第三磨牙根据不同粘接剂[Optibond Versa(OV),All-bond Universal(AU),Single Bond Universal(SU),Adper Easy One(AEO)]随机分为4组。每种粘接剂组各半分别使用酸蚀-冲洗和自酸蚀的模式。牙齿与复合树脂粘接后一半样本储存于37℃纯水中24 h,另一半经5000次冷热循环老化实验。沿长轴将牙齿切割成约0.9 mm×0.9 mm柱状试件,测试其微拉伸强度,使用三因素方差分析法分析结果。未经冷热循环各组取切片于扫描电镜下观察粘接界面。结果:冷热循环、酸蚀模式分别与粘接剂种类因素存在两因素交互作用,经过冷热循环后和使用自酸蚀处理时3种通用型粘接剂的微拉伸强度均优于AEO(P<0.001)。未经冷热循环时,OV、AU的微拉伸强度均>AEO;OV的微拉伸强度>SU。采用酸蚀-冲洗模式处理时,AU的微拉伸强度>AEO,AU的微拉伸强度>SU。结论:通用型粘接剂的微拉伸强度整体要优于第7代粘接剂,尤其是经过冷热循环后和自酸蚀处理时优势更明显。Objective:This study aims to evaluate the instant and after thermocycling micro-tensile bond strength(μTBS)of three universal dentin adhesives and one 7 th generation dentin adhesive under etch-rinse and self-etch strategies.Methods:Total 128 noncarious human third molars were randomly divided into 4 equal groups based on the dentin adhesives(Optibond Versa(OV),All-bond Universal(AU),Single Bond Universal(SU),Adper Easy One(AEO)).Two bonding modes(etch-rinse and self-etch)were employed for each half of each adhesive group.After bounding with resin,half of the specimens were stored in distilled water at 37℃for 24 h and the other half were underwent a 5000-cycle thermocycling ageing process.Along the long axis,the dentin-resin bonded teeth were sectioned into approximately 0.9 mm×0.9 mm specimens for the micro-tensile bond strength(μTBS)test.Statistical analyses were computed using three-way ANOVA.The resin-dentin interfaces of non-thermocycled specimens were observed by scanning electron microscopy(SEM).Results:There were 2-factors interactions between thermocycling and adhesives,etch modes and adhesives.After thermocycling or under self-etch strategie,3 universal adhesives had higherμTBS than AEO(P<0.001).While without thermocycling,theμTBS of OV and AU were higher than AEO,and theμTBS of OV were higher than SU.TheμTBS of AU were higher than AEO and SU when under the etch-rinse strategy.Conclusion:Universal adhesives in this study had higherμTBS than the7 th generation adhesive,especially after thermocycling or under self-etch strategy.

关 键 词：通用型粘接剂 牙本质粘接 微拉伸强度 酸蚀-冲洗 自酸蚀 

分 类 号：K783.3[历史地理—历史学]