宫氏脑针治疗癌性疼痛的临床研究  

Clinical Study on Treatment of Cancerous Pain with GONG’s Cranial Acupuncture

作　　者：游敏玲 谢栋 谌玉佳 李敏 徐舒 YOU Min-Ling;XIE Dong;SHEN Yu-Jia;LI Min;XU Shu(Shenzhen Luohu District Hospital of Traditional Chinese Medicine,Shenzhen 518000 Guangdong,China;The 74th Group Army Hospital,Guangzhou 510318 Guangdong,China;Shenzhen Hospital(Guangming branch),University of Chinese Academy of Sciences,Shenzhen 518000 Guangdong,China)

机构地区：[1]深圳市罗湖区中医院,广东深圳518000 [2]陆军第七十四集团军医院,广东广州510318 [3]中国科学院大学深圳医院(光明),广东深圳518000

出　　处：《广州中医药大学学报》2020年第8期1480-1485,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药局科研课题(编号:20191282)。

摘　　要：【目的】探讨宫氏脑针疗法联合三阶梯药物止痛法治疗癌性疼痛的临床疗效。【方法】将60例住院治疗的癌痛患者随机分为治疗组和对照组,每组各30例。2组患者均使用三阶梯止痛药物治疗,在此基础上,治疗组给予宫氏脑针治疗,连续治疗14 d。观察2组患者治疗前后疼痛程度数字评分量表(NRS)评分和生活质量Karnofsky功能状态评分(KPS)的变化情况及全程等效吗啡使用量,评价2组患者的疼痛缓解疗效和安全性。【结果】(1)治疗后,治疗组患者的疼痛缓解总有效率为80.0%(24/30),明显高于对照组的53.3%(16/30),差异有统计学意义(P<0.05)。(2)治疗后,2组患者的疼痛强度NRS评分较治疗前均降低(P<0.05),且治疗组治疗后的疼痛强度NRS评分明显低于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的生活质量KPS评分均较治疗前明显提高(P<0.05),且治疗组治疗后的生活质量KPS评分明显高于对照组,差异有统计学意义(P<0.01)。(4)治疗组患者的治疗全程等效吗啡使用量明显少于对照组,差异有统计学意义(P<0.01)。(5)治疗过程中,2组患者均有不同程度的恶心、呕吐、便秘、乏力、头晕等不良反应,治疗组的不良反应发生率均明显低于对照组,差异均有统计学意义(P<0.05或P<0.01)。【结论】宫氏脑针联合三阶梯药物止痛疗法治疗癌性疼痛疗效确切,可有效提高癌痛缓解率,减少全程等效吗啡使用量,降低不良反应发生率,提高患者生活质量,其疗效优于单纯使用三阶梯药物止痛法。Objective To investigate the clinical effect of GONG’s cranial acupuncture combined with three-step analgesic ladder therapy for the management of cancerous pain. Methods Sixty cases of inpatients with cancerous pain were randomly divided into treatment group and control group,with 30 cases in each group. The patients of the two groups were treated with three-step analgesic ladder therapy,and additionally,the treatment group was given GONG’s cranial acupuncture. The treatment lasted for 14 continuous days. Before and after treatment,we observed the scores of pain degree evaluated with numerical rating scale(NRS), the scores of quality of life evaluated with Karnofsky Performance Status(KPS), and morphine consumption throughout the trial for the evaluation of clinical efficacy for the relief of pain and the clinical safety in the two groups. Results(1)After treatment,the total effective for the pain relief in the treatment group was 80.0%(24/30),and was obviously higher than that in the control group(53.3%,16/30),the difference being statistically significant(P<0.05).(2)After treatment, the NRS scores of both groups were decreased as compared with those before treatment(P<0.05),and the scores of the treatment group were lower than those of the control group(P < 0.05).(3)After treatment,the KPS scores for the quality of life in the two groups were increased as compared with those before treatment(P<0.05), and the scores of the treatment group were higher than those of the control group, the difference being statistically significant(P < 0.01).(4) The total amount of morphine consumption throughout the trial in the treatment group was significantly less than that in the control group,the difference being statistically significant(P < 0.01).(5)During the trial, the incidence of adverse reactions such as nausea, vomiting,constipation,weakness,and vertigo in the treatment group was significantly lower than that in the control group(P < 0.05 or P<0.01). Conclusion GONG’s cranial acupuncture combined with three-ste

关 键 词：癌性疼痛 宫氏脑针疗法 三阶梯药物止痛法 针刺止痛 

分 类 号：R246.5[医药卫生—针灸推拿学]