骨导听性脑干反应和骨导多频听觉稳态反应在传导性听力损失检测中的应用  

Application of bone conduction auditory brainstem response and auditory steady-state response in assessment of conductive hearing loss

作　　者：楼高忠 胡娟[2] 史文迪 LOU Gaozhong;HU Juan;SHI Wendi(Department of Otorhinolaryngology,Hangzhou Children's Hospital,Hangzhou 310014,China;Department of Otorhinolaryngology,Head and Neck Surgery,the 2nd Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China;Department of Audiology,Zhejiang Chinese Medical University,Hangzhou 310053,China;Clinical Audiology Institute of Hangzhou Ren'ai Deaf Rehabilitation Research Institute,Hangzhou 310004,China)

机构地区：[1]浙江省杭州市儿童医院耳鼻咽喉科,杭州310014 [2]西安交通大学第二附属医院耳鼻咽喉头颈外科,西安710004 [3]浙江中医药大学听力学系,杭州310053 [4]杭州仁爱耳聋康复研究院临床听力学研究所,杭州310004

出　　处：《中国眼耳鼻喉科杂志》2020年第4期301-304,共4页Chinese Journal of Ophthalmology and Otorhinolaryngology

基　　金：国家自然科学基金(81600809);陕西省自然科学基础研究计划(2018JQ8001);中央高校基本科研业务费(xjj2018279);西安交通大学第二附属医院人才培养专项科研基金[RC(GG)201802]。

摘　　要：目的研究骨导分频率听性脑干反应(BC-chirp-ABR)和骨导多频听觉稳态反应(BC-ASSR)与骨导纯音听阈(BC-PTA)在传导性听力损失患者中的差异和相关性,为临床客观听力诊断及预估主观测听阈值提供参考。方法对40例单侧传导性听力损失患者分别行掩蔽后的BC-chirp-ABR和BC-ASSR测试,获得反应阈,并与BC-PTA阈值进行相关性分析。结果在0.5、1、2、4 kHz频率,BC-chirp-ABR反应阈分别为(25.0±8.2)、(22.3±6.1)、(18.2±7.6)、(19.7±6.9)dB nHL,BC-ASSR反应阈分别为(30.7±10.1)、(28.3±9.7)、(27.7±9.1)、(27.1±8.6)dB nHL。在上述4个频率,BC-PTA阈值分别为(9.5±6.3)、(10.7±5.7)、(12.8±9.1)、(15.3±4.5)dB HL。Pearson相关性分析显示,BC-chirp-ABR和BC-ASSR反应阈与同频率BC-PTA阈值均具有显著相关性,频率越高相关性越强。结论BC-chirp-ABR和BC-ASSR能够反映同频率BC-PTA阈值,BC-chirp-ABR和BC-ASSR是较好评估主观听阈的频率特异性客观测听技术。Objective To evaluate the difference and the correlationship between bone conduction chirp evoked auditory brainstem response(BC-chirp-ABR),bone conduction auditory steady-state response(BC-ASSR)thresholds and bone conduction pure tone auditory(BC-PTA)thresholds,and to set up assessments for objective audiometry in patients with conductive hearing loss.Methods BC-chirp-ABR and BC-ASSR were performed in 40 patients with conductive hearing loss.The evoked-potential thresholds were obtained and compared with BC-PTA thresholds.Results At the frequents of 0.5,1,2,4 kHz,the thresholds of BC-chirp-ABR were 25.0±8.2,22.3±6.1,18.2±7.6,19.7±6.9 dB nHL;whereas the thresholds of BC-ASSR were 30.7±10.1,28.3±9.7,27.7±9.1,27.1±8.6 dB nHL,respectively.At the above 4 frequents,the thresholds of BC-PTA were 9.5±6.3,10.7±5.7,2.8±9.1,15.3±4.5 dB HL.Pearson correlationship analysis suggested that BC-chirp-ABR and BC-ASSR thresholds had high correlations with BC-PTA thresholds at each frequent,and higher correlations were detected at higher frequents.Conclusions BC-chirp-ABR and BC-ASSR provided rationally accurate predictions of multi-frequencies objective audiometry by taking the accuracy predicted BC-PTA thresholds.

关 键 词：骨导 短纯音听性脑干反应 多频听觉稳态反应 阈值 传导性聋 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]