特发性嗜酸粒细胞增多综合征1例并文献复习  

Idiopathic hypereosinophilic syndrome:a case report and literature review

作　　者：叶丽[1] 高灵素 丁美琪[1] 虞国慧[1] 冯学艺 YE Li;GAO Lingsu;DING Meiqi;YU Guohui;FENG Xueyi(Department of Hematology,The Lu’an People’s Hospital,Lu’an,Anhui 237005,China;Department of Vascular Surgrey,The Lu’an People’s Hospital,Lu’an,Anhui 237005,China)

机构地区：[1]六安市人民医院血液内科,安徽六安237005 [2]六安市人民医院血管外科,安徽六安237005

出　　处：《安徽医药》2020年第8期1574-1576,I0004,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的提高对特发性嗜酸粒细胞增多综合征的认识。方法报告2015年10月9日六安市人民医院收治的特发性嗜酸细胞增多综合征1例,观察其临床表现及治疗经过,并进行文献复习。结果病人出现消化、神经、皮肤等多个系统损害,经激素治疗后好转,自行停药后,出现右侧肢体动静脉血栓,激素联合环磷酰胺治疗后病情改善。结论特发性嗜酸粒细胞增多综合征可以累及消化、神经、心血管、皮肤等多个系统,可以导致血栓形成等并发症,严重时可危及生命,早期诊断及治疗尤为重要。Objective pathic hypereosinophilic syndrome,who received treatment in The Lu’an People’s Hospital in October 9,2015,was selected.Its clinical manifestations and treatment were observed,and literature review was carried out.Results The patient developed damage to digestive system,nervous system and dermal system,which was improved after hormone therapy.After self-withdrawal of medication,the patient developed arteriovenous thrombosis of the right limb,which was improved after hormone therapy combined with cyclophosphamide.Conclusion Idiopathic hypereosinophilic syndrome can involve multiple systems,such as digestive,nervous,cardiovascular and dermal systems,and can lead to complications such as thrombosis.In severe cases,it can be life-threatening.Early diagnosis and treatment are especially important.

关 键 词：嗜酸粒细胞增多肌痛综合征 多系统损害 糖皮质激素 环磷酰胺 

分 类 号：R557.3[医药卫生—血液循环系统疾病]