人体成分相关指标与动脉硬化的相关性研究  

Correlation between body composition and arteriosclerosis

作　　者：杨雪雪 毛开敏 张存泰[1] 阮磊 YANG Xue-xue;MAO Kai-min;ZHANG Cun-tai;RUAN Lei(Department of Geriatrics,Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院老年科,湖北省武汉市430030

出　　处：《实用老年医学》2020年第7期695-698,共4页Practical Geriatrics

基　　金：湖北省重大科技创新基金项目(2019ACA141)。

摘　　要：目的研究人体成分相关指标与动脉硬化的相关性。方法对2016年6月至2017年3月514例体检人群进行人口学资料、心血管疾病危险因素调查,应用人体成分分析仪记录身高、体质量、BMI、体脂肪率、体脂肪量、肌肉量、内脏脂肪水平、身体年龄等指标。检测体检者臂踝动脉脉搏波传导速度(baPWV)。人体成分指标与baPWV的相关分析采用Pearson相关分析与偏相关分析。结果Pearson相关分析显示:身体年龄、内脏脂肪水平、体脂肪率、体脂肪量、BMI与baPWV呈正相关,肌肉量比值与baPWV呈负相关。控制年龄、SBP、DBP后,经偏相关分析结果显示,身体年龄仍与baPWV呈正相关。按年龄分组后Pearson相关分析结果显示:在30~44岁人群中,内脏脂肪水平与baPWV相关性最大(r=0.34,P<0.01);在45~59岁人群中,身体年龄与baPWV相关性最大(r=0.38,P<0.01);60岁以上人群中,身体年龄与baPWV相关性最大(r=0.53,P<0.01)。结论中心性肥胖与动脉硬化的相关性更密切;身体年龄的增加可以作为动脉硬化的预测因子,增加肌肉量比值可能延缓动脉硬化。随着年龄的增加,内脏脂肪水平与动脉硬化的相关性逐渐减弱;60岁以上人群内脏脂肪水平与动脉硬化没有相关性。Objective To study the correlation between body composition and arteriosclerosis.Methods Demographic data and risk factors of cardiovascular diseases were investigated in 514 subjects who underwent physical examination from June 2016 to March 2017.Height,weight,body mass index(BMI),body fat rate,body fat volume,muscle mass,the level of visceral fat and body age were recorded by body composition analyzer.Brachial-ankle pulse wave velocity(baPWV)was detected by OMRON arteriosclerosis detector(VP-1000).The correlation of body composition with baPWV was analyzed by Pearson correlation analysis and partial correlation analysis.Results Pearson correlation analysis showed that body age,visceral fat level,body fat rate,body fat mass and BMI were positively correlated with baPWV(P<0.05).The ratio of muscle mass to weight was negatively correlated with baPWV(P<0.05).After adjusting for age,systolic blood pressure and diastolic blood pressure,partial correlation analysis showed that body age was still positively correlated with baPWV(P<0.05).According to Pearson correlation analysis by age subgroup,the correlation between visceral fat level and baPWV was the most significant in the group aged 30 to 44(r=0.34,P<0.01),and the correlation between body age and baPWV was the most significant in the group aged 45 to 59(r=0.38,P<0.01),and in the group aged over 60(r=0.53,P<0.01).Conclusions The correlation between central obesity and arteriosclerosis is closer than BMI.The increase of body age can be used as a predictor of arteriosclerosis.Increased muscle mass ratio may delay the progress of atherosclerosis.With the increase of age,the correlation between visceral fat level and arteriosclerosis is gradually weakened.And visceral fat level is not associated with arteriosclerosis in people aged over 60 years old.

关 键 词：人体成分 体质量指数 内脏肥胖 身体年龄 动脉硬化 相关性分析 

分 类 号：R543.5[医药卫生—心血管疾病]