以肠套叠为首发表现的儿童非霍奇金淋巴瘤8例  

Clinical cases analysis of non-Hodgkin lymphoma with intussusception as the first presentation

作　　者：潘俊涛[1] 张大[1] 崔西春[1] 张蛟[1] 张春英[1] 谢潭 范应中[1] 王家祥[1] PAN Juntao;ZHANG Da;CUI Xichun;ZHANG Jiao;ZHANG Chunying;XIE Tan;FAN Yingzhong;WANG Jiaxiang(Department of Pediatric Surgery,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052)

机构地区：[1]郑州大学第一附属医院小儿外科,郑州450052

出　　处：《郑州大学学报（医学版）》2020年第4期560-563,共4页Journal of Zhengzhou University(Medical Sciences)

基　　金：河南省医学科技攻关计划省部共建项目(SB201903007)。

摘　　要：目的:探讨以肠套叠为首发表现的儿童非霍奇金淋巴瘤(NHL)的临床特征及诊治特点。方法:对郑州大学第一附属医院2013年1月至2018年12月收治的入院诊断为肠套叠且出院诊断包含“淋巴瘤”的8例患儿进行回顾性分析。结果与结论:8例NHL患儿以肠套叠为首发表现,均行空气灌肠复位失败,急诊手术探查行局部病灶切除。术后病理诊断Burkitt淋巴瘤4例,弥漫性大B细胞淋巴瘤4例,均在病理明确诊断及分期后行规范化疗。8例患儿均恢复良好,未见肠梗阻、吻合口瘘和吻合口狭窄等并发症。随访9~71个月,未见肿瘤复发者。对于非典型发病年龄或反复发作的肠套叠,以及术中发现肠壁包块或套叠肠壁异常僵硬的肠套叠,应注意由NHL引起继发性肠套叠的可能。Aim:To investigate the clinical characteristics and diagnosis and treatment of non-Hodgkin lymphoma(NHL)in children with intussusception as the first manifestation.Methods:A retrospective analysis was made on 8 children with intussusception and lymphoma from January 2013 to December 2018 in the First Affiliated Hospital of Zhengzhou University.Results and Conclusion:Intussusception was the first manifestation in 8 children with NHL.Air enema failed in reduction,and local resection was performed successfully for each case in emergency operation.Pathological examination revealed 4 cases of Burkitt lymphoma,and 4 cases of diffuse large B cell lymphoma.All cases were treated with standard chemotherapy after pathological diagnosis and staging.During the follow-up of 9~71 months,no tumor recurrence had beenfound in these 8 cases.For children with recurrent intussusception or episode at atypical age,and abnormal mass on intestinal wall or abnormal stiffness of the intestinal wall during the operation,NHL should be concerned.

关 键 词：儿童 肠套叠 非霍奇金淋巴瘤 

分 类 号：R725.5[医药卫生—儿科]