微创穿刺引流术联合尿激酶与开颅血肿清除方法对高血压基底节区出血患者预后情况探讨  

Prognosis of Minimally Invasive Puncture and Drainage Combined with Urokinase and Craniotomy in Patients with Hypertensive Basal Ganglia Hemorrhage

作　　者：黄沃斌 吕建光 李柱辉 HUANG Wo-bin;LYU Jian-guang;LI Zhu-hui(Department of Neurosurgery,Dongguan Dalang Hospital,Dongguan,Guangdong Province,523770 China)

机构地区：[1]东莞市大朗医院神经外科,广东东莞523770

出　　处：《中外医疗》2020年第14期62-64,共3页China & Foreign Medical Treatment

摘　　要：目的探讨微创穿刺引流术联合尿激酶与开颅血肿清除方法对高血压基底节出血患者预后的影响。方法方便选取2014年11月—2016年10月在该院接受治疗的高血压基底节区出血患者90例,采用随机数表法将患者分为观察组(45例)和对照组(45例),对照组患者给予常规治疗,观察组患者给予微创穿刺引流术联合尿激酶的方法治疗。比较两组患者的手术情况,治疗后并发症发生率及患者生活质量改善情况。结果观察组患者的GCS评分(11.56±2.89)分、血肿清除率(56.12±10.45)%高于对照组(8.12±2.56)分、(50.23±9.21)%,住院时间(15.78±3.89)d、引流管放置时间(3.89±0.56)d短于对照组(17.98±4.02)d、(5.80±1.02)d,两组差异有统计学意义(t=5.977、2.638、2.837、11.011,P<0.001);观察组总并发症发生率20.0%低于对照组57.8%,两组差异有统计学意义(χ^2=13.511,P<0.001);观察组患者生活质量精神健康(53.23±5.02)分、总体健康(78.56±9.56)分等显著高于对照组(46.56±8.23)分、(65.45±10.23)分,两组差异有统计学意义(t=4.641、6.281,P<0.001)。结论给予微创穿刺引流术联合尿激酶与开颅血肿清除方法治疗高血压基底节区出血患者,能够有效改善患者的神经功能,降低并发症的发生。Objective To investigate the effect of minimally invasive puncture and drainage combined with urokinase and craniotomy on the prognosis of patients with hypertension basal ganglia hemorrhage.Methods Ninety patients with hypertensive basal ganglia bleeding who were treated in the hospital from November 2014 to October 2016 were convenienty selected,and the patients were divided into observation group(45 cases)and control group(45 cases)by random number table method.Patients in the control group were given conventional treatment,and patients in the observation group were given minimally invasive puncture and drainage combined with urokinase.The surgical conditions,the incidence of complications,and the improvement of patients'quality of life were compared between the two groups.Results The GCS score(11.56±2.89)points,hematoma clearance(56.12±10.45)%of the observation group were higher than that of the control group(8.12±2.56)points,(50.23±9.21)%,hospital stay(15.78±3.89)d,drainage tube The storage time(3.89±0.56)d was shorter than that of the control group(17.98±4.02)d and(5.80±1.02)d,and the difference between the two groups was statistically significant(t=5.977,2.638,2.837,11.011,P<0.001);the total concurrency in the observation group The incidence of disease was 20%lower than that of the control group,57.8%.The difference between the two groups was statistically significant(χ^2=13.511,P<0.001);the quality of life of the observation group was mental health(53.23±5.02)points,overall health(78.56±9.56)points,etc.It was significantly higher than the control group(46.56±8.23)points and(65.45±10.23)points,and the differences between the two groups were statistically significant(t=4.641,6.281,P<0.001).Conclusion Minimally invasive puncture and drainage combined with urokinase and craniotomy for hematoma removal in patients with hypertension basal ganglia hemorrhage can effectively improve the neurological function of patients and reduce the occurrence of complications.

关 键 词：微创穿刺引流术 尿激酶 血肿清除术 高血压 基底节区出血 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]