慢性鼻窦炎内镜术中使用可吸收鼻窦药物支架的疗效分析  

Efficacy analysis of use of absorbable sinus drug stents in functional endoscopic sinus surgery

作　　者：万玉峰[1] 刘龙生[1] 徐盼盼 高俊康 WAN Yufeng;LIU Longsheng;XU Panpan;GAO Junkang(Department of Otorhinolaryngology Head and Neck Surgery, the Affiliated Chaohu Hospital of Anhui Medical University,Heifei,238000,China)

机构地区：[1]安徽医科大学附属巢湖医院耳鼻咽喉头颈外科,合肥238000

出　　处：《临床耳鼻咽喉头颈外科杂志》2020年第5期417-420,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨功能性内镜鼻窦手术(FESS)术中置入可吸收鼻窦药物支架治疗慢性鼻窦炎的疗效。方法:将107例拟行FESS的慢性鼻窦炎患者分成支架组58例和非支架组49例,支架组术中使用鼻窦药物支架;非支架组术中未使用鼻窦药物支架。2组接受相同的术后治疗。术后随访1个月,术后3个月复查。疗效主要通过内镜检查评估,评估指标包括鼻窦黏膜是否充血水肿、中鼻甲有无黏连、有无囊泡或息肉样变黏膜形成、窦口有无狭窄或再次闭塞、鼻窦黏膜是否上皮化和术后是否干预6项。结果:支架组58例患者成功植入支架。术后1个月上述6项指标在支架组与非支架组之间的差异均有统计学意义,支架组术后并发症发生率及术后干预率均明显低于非支架组(均P<0.01),支架组鼻窦黏膜上皮化发生率明显高于非支架组(P<0.01)。术后3个月复查2组均全部完成鼻窦黏膜上皮化,而支架组术后并发症发生率及术后干预率仍均明显低于非支架组(P<0.05或P<0.01)。结论:FESS术中置入可吸收鼻窦药物支架治疗慢性鼻窦炎效果安全理想,在有效缓解鼻窦炎患者临床症状的同时能进一步控制并发症的产生。Objective:To explore the efficacy of functional endoscopic sinus surgery(FESS)with an absorbable sinus drug stent in the treatment of chronic sinusitis.Method:107 patients with chronic sinusitis who underwent FESS were divided into two groups:58 patients were set as stent group who were treated with sinus drug elution during surgery;49 patients who did not receive a sinus drug stent were included in the non-stent group.The same postoperative treatment were used in the two groups.The patients were followed up for 1 month and reviewed 3 months after surgery.Efficacy is mainly evaluated by endoscopy.The evaluation indicators include whether the sinus mucosa is congested and edema,whether there is adhesion in the middle turbinate,whether vesicles or polyp-like mucosa are formed,whether the sinus mouth is stenosed or reoccluded,whether the sinus mucosa is epithelialized,and whether the patient had intervention after surgery.Result:Stents were successfully implanted in 58 patients in the stent group.The difference of the above six indexes between the stent group and the non-stent group was statistically significant at 1 month after operation.The postoperative complication rate and postoperative intervention rate were significantly lower in the stent group than in the control group(P<0.01),the incidence of sinus mucosal epithelialization in the stent group was significantly higher than that in the non-stent group(P<0.01).The sinus mucosal epithelialization were all completed in both groups after 3 months of surgery.The postoperative complication rate and postoperative intervention rate were significantly lower in the stent group than in the non-stent group(P<0.05 or P<0.01).Conclusion:FESS combined with the absorption of sinus drug stents for the treatment of chronic sinusitis is safe and effective which can control the complications further after surgery while relieving the clinical symptoms of patients with sinusitis effectively.

关 键 词：鼻窦炎 内镜术 可吸收鼻窦药物支架 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]