水热法制备羟基磷灰石涂层包覆镁合金的耐腐蚀性能和快速矿化能力  

Corrosion Resistance and Rapid Mineralization of Hydroxyapatite Coated Magnesium Alloy Prepared by Hydrothermal Method

作　　者：孙佳月 蔡舒[1] 韦洁玲 刘佳[2] 许国华[2] SUN Jiayue;CAI Shu;WEI Jieling;LIU Jia;XU Guohua(Key Laboratory of Advanced Ceramics and Machining Technology,Ministry of Education,Tianjin University,Tianjin 300072,China;Changzheng Hospital of Second Military Medical University,Shanghai 200003,China)

机构地区：[1]天津大学先进陶瓷与机械加工技术教育部重点实验室,天津300072 [2]第二军医大学长征医院,上海200003

出　　处：《硅酸盐学报》2020年第6期810-817,共8页Journal of The Chinese Ceramic Society

基　　金：国家自然科学基金(51872197,51572186)。

摘　　要：生物镁合金在骨组织修复中具有良好的应用潜力,但生理条件下极易受到腐蚀,失去原有的力学性能,导致植入体在服役过程中失效。为了提高其耐蚀性能和快速诱导磷灰石的能力,采用一步水热法在镁合金上制备了微纳结构的羟基磷灰石涂层,涂层极化阻抗值达到138.680 k?·cm^2,具有优异的电化学性能。在模拟体液中测试试样30 d内的体外降解性能,溶液的pH值稳定在7.10~7.60之间,腐蚀速率始终低于0.400 mm/y。在浸泡3 d时,涂层表面由羟基磷灰石形成,微纳结构能快速诱导Ca–P产物的沉积,具有良好的矿化能力。Magnesium alloy has good potential application in bone tissue repair,but it is extremely susceptible to corrosion in the human physiological environment and loses its original mechanical properties,causing the implant material to fail during service.In order to improve its corrosion resistance and ability to rapidly induce apatite in vitro,a one-step hydrothermal method was used to prepare a micro-nano structured hydroxyapatite coating on magnesium alloys.The polarization resistance of the sample reached 138.680 k?·cm^2,indicating that the sample has excellent electrochemical performance.The degradation performance of the sample was tested in simulated body fluids.During the 30 d immersion time,the pH value of the simulated body fluids were maintained in the range of 7.10–7.60,and the corrosion rate was lower than 0.400 mm/y.And when immersed for 3 d,hydroxyapatite mineralization were formed on the coating surface,indicating that the micro-nano structural coating can quickly induce the formation of Ca–P products and has good mineralization ability.

关 键 词：镁合金 羟基磷灰石 涂层 耐腐蚀性能 矿化能力 

分 类 号：R318.08[医药卫生—生物医学工程]