中医综合疗法治疗日本籍视网膜色素变性297例回顾性分析  

Retrospective Analysis of Traditional Chinese Medicine Comprehensive Therapy for 297 Cases of Japanese Retinitis Pigmentosa

作　　者：彭俊[1] 杨毅敬 李波[1] 张健[1] 张明亮[1] 喻京生[1] 朱有章 李传课[1] 彭清华[1,2] PENG Jun;YANG Yijing;LI Bo;ZHANG Jian;ZHANG Mingliang;YU Jingsheng;ZHU Youzhang;LI Chuanke;PENG Qinghua(Department of Ophthalmology,The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha,Hunan 410007,China;Hunan University of Chinese Medicine,Changsha,Hunan 410208,China)

机构地区：[1]湖南中医药大学第一附属医院眼科,湖南长沙410007 [2]湖南中医药大学,湖南长沙410208

出　　处：《湖南中医药大学学报》2020年第7期788-791,共4页Journal of Hunan University of Chinese Medicine

基　　金：国家自然科学基金项目(81804150);湖南省自然科学基金项目(2019JJ40226);湖南省教育厅创新平台开放基金项目(16K065);湖南省研究生创新基金项目(CX2018B497);湖南省科学技术委员会科研基金项目(90-23-004-2);中医五官科学湖南省重点学科、中医眼科学国家中医药管理局重点学科资助项目;中央财政支持地方高校重点学科建设项目。

摘　　要：目的回顾性整理采用中医综合疗法治疗日本籍视网膜色素变性患者297例594只眼的临床疗效。方法采用中医辨证论治,辨证分为肾阳不足、肝肾阴虚、脾气虚弱、气虚血瘀4个证型,分别采用温补肾阳、活血明目,滋补肝肾、活血明目,补脾益气、活血明目,益气活血、化瘀明目的治法,给予右归丸、明目地黄丸、补中益气汤、补阳还五汤加减、针灸治疗、耳穴贴压、穴位注射、辨证使用中成药等中医综合治法,观察治疗前后日本籍视网膜色素变性患者的视力、视野改善情况。结果视力方面:显效121只眼,有效343只眼,无效130只眼,总有效率为78.12%。视野方面:显效108只眼,有效294只眼,无效192只眼,总有效率为67.68%。患者治疗后视力与视野较治疗前明显提高,差异有统计学意义(P<0.01)。结论中医综合疗法能有效治疗日本籍视网膜色素变性患者,能提高患者的视力,并扩大视野。Objective To retrospectively analyze the clinical efficacy of traditional Chinese medicine(TCM) comprehensive therapy in the treatment of 594 eyes of 297 Japanese patients with retinitis pigmentosa.Methods TCM syndrome differentiation and treatments were adopted.Syndromes were differentiated into kidney Yang insufficiency syndrome, liver and kidney Yin deficiency syndrome, deficiency and weakness of spleen Qi syndrome, Qi deficiency and blood stasis syndrome.They were respectively treated with warming and nourishing kidney Yang, activating blood circulation for improving eyesight;nourishing the liver and kidney,activating blood circulation for improving eyesight;fortifying the spleen and replenishing Qi, activating blood circulation for improving eyesight;and tonifying Qi and activating blood circulation, resolving stasis for improving eyesight.Comprehensive TCM therapies including Yougui Pills, Mingmu Dihuang Pills, Buzhong Yiqi Decoction, Modified Buyang Huanwu Decoction,acupuncture, auricular point pressing, acupoint injection, and Chinese materia medica based on syndrome differentiation.The visual acuity and visual field improvement of Japanese patients with retinitis pigmentosa were observed before and after treatment.Results In terms of visual acuity: 121 eyes were markedly effective, 343 were effective, 130 eyes were ineffective, and the total effective rate was 78.12%.In terms of visual field: 108 eyes were markedly effective, 294 eyes were effective, and 192 eyes were ineffective.The total effective rate was 67.68%, the difference was statistically significant(P<0.01).Conclusion TCM comprehensive therapy is effective in treating Japanese retinitis pigmentosa, which can improve patients’ vision and expand their visual fields.

关 键 词：视网膜色素变性 温补肾阳 活血明目 补脾益气 耳穴贴压 穴位注射 

分 类 号：R276.7[医药卫生—中医五官科学]