应用超声心动图斑点追踪技术评价射血分数保留型心力衰竭患者的左心室收缩功能  

Role of speckle tracking echocardiography in assessment of left ventricular systolic function in patients with heart failure with preserved ejection fraction

作　　者：肖兆良 黄彦生 Xiao Zhaoliang;Huang Yansheng(Department of Cardiology,People’s Hospital of Zhengzhou University,Henan Provincial People’s Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州大学人民医院,河南省人民医院心血管内科,450000

出　　处：《中国实用医刊》2020年第7期10-13,共4页Chinese Journal of Practical Medicine

基　　金：河南省科技厅基金项目(CKQ201500034)。

摘　　要：目的应用斑点追踪技术评价射血分数保留型心力衰竭(HFpEF)患者的左心室心肌收缩功能,并探讨其临床意义。方法选取2018年9月至2019年9月因心力衰竭入住河南省人民医院心内科的患者42例,其中21例HFpEF患者作为HFpEF组,21例射血分数降低型心力衰竭(HFrEF)患者作为HFrEF组,另选取年龄、危险因素等相近的左室舒张功能减退患者15例作为对照组。比较三组患者的临床资料,并采用斑点追踪技术测量其左心室纵向峰值应变(GLS)和峰值应变离散度(PSD),并进行统计分析。结果①HFpEF组GLS和PSD值与HFrEF组及对照组相比,差异有统计学意义(P<0.05)。②GLS、PSD值方面,对照组<HFpEF组<HFrEF组,P<0.05。③对HFpEF组患者进行Pearson相关分析显示,GLS和PSD均与氨基末端脑钠肽前体(NT-proBNP)存在相关性,r分别为0.50和0.40,P均<0.05。结论GLS和PSD对左心室收缩功能具有评价意义,虽然HFpEF患者的左心室射血分数正常,但大多存在左心室收缩功能障碍。Objective To investigate the clinical significance of speckle track echocardiography in assessing the myocardial systolic function of the left ventricle in patients with heart failure with preserved ejection fraction(HFpEF).Methods A total of 42 patients with heart failure treated in Henan Provincial People’s Hospital from September 2018 to September 2019 were selected and divided into two groups:21 patients with HFpEF treated as HFpEF group,and 21 patients with heart failure with reduced ejection fraction(HFrEF)treated as HFrEF group.And 15 patients with reduced left ventricular diastolic function,which had similar age and risk factors,were selected as the control group.The clinical data of the three groups were compared.The global longitudinal strain(GLS)and peak strain dispersion(PSD)of the left ventricle were measured by speckle tracking technology,and they were analyzed by statistical method.Results①The GLS and PSD values of HFpEF group were significantly different from those of HFrEF group and control group(P<0.05).②The GLS and PSD values of HFrEF group were the highest,followed by HFpEF group and control group sequentially,P<0.05.③Pearson correlation analysis for the HFpEF group showed that both GLS and PSD were correlated with N-terminalpro-brain natriuretic peptide precursor(NT-proBNP),with r=0.50,0.40,respectively,all P<0.05.Conclusions GLS and PSD have significance in assessing left ventricular systolic function.The left ventricular ejection fractions of HFpEF patients are normal,but most of patients have left ventricular systolic dysfunction.

关 键 词：心力衰竭 斑点追踪超声心动图 左心室整体纵向应变 峰值应变离散度 左心室收缩功能 

分 类 号：R541[医药卫生—心血管疾病]